Partitioning of Catechol Derivatives in Lipid Membranes: Implications for Substrate Specificity to Catechol- O-methyltransferase

Biochemistry, Genetics and Molecular Biology

• Octanol 100%
• Enzyme Specificity 100%
• Partition Coefficient 100%
• Neurotransmitter 66%
• 3-Methoxytyramine 66%
• Metabolic Pathway 33%
• Small Molecule 33%
• Artificial Membrane 33%
• Lipophilicity 33%
• Isoform 33%
• Membrane-Bound Enzyme 33%
• Phosphatidylcholine 33%
• Surface Plasmon Resonance 33%
• Cell Membrane 33%

Keyphrases

• Catechol Derivatives 100%
• Catechol-O-methyltransferase 100%
• Lipid Membrane 100%
• 3-methoxytyramine 66%
• Lipid Affinity 33%
• Outer Leaflet 33%
• Enzyme Affinity 33%
• Membrane Modeling 33%
• Octanol-water 33%
• Spontaneous Excitatory Postsynaptic Current (sEPSC) 33%
• Neurotransmitter Dopamine 33%
• Membrane Enzymes 33%
• Total Lipids 33%
• Water System 33%
• Methyl Derivatives 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Methyltransferase 100%
• Catechol Derivative 100%
• Membrane Lipid 100%
• Neurotransmitter 66%
• 3 O Methyldopamine 66%
• Membrane Enzyme 33%