Novel plasma protein binding analysis method for a PET tracer and its radiometabolites: A case study with [C-11]SMW139 to explain the high uptake of radiometabolites in mouse brain

R Aarnio; OM Alzghool; S Wahlroos; J O'Brien-Brown; M Kassiou; O Solin; JO Rinne; S Forsback; M Haaparanta-Solin

doi:10.1016/j.jpba.2022.114860

Novel plasma protein binding analysis method for a PET tracer and its radiometabolites: A case study with [C-11]SMW139 to explain the high uptake of radiometabolites in mouse brain

R Aarnio, OM Alzghool, S Wahlroos, J O'Brien-Brown, M Kassiou, O Solin, JO Rinne, S Forsback, M Haaparanta-Solin

Turku PET Centre

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

3 Sitaatiot (Scopus)

36 Lataukset (Pure)

Alkuperäiskieli	Englanti
Artikkeli	114860
Sivumäärä	9
Julkaisu	Journal of Pharmaceutical and Biomedical Analysis
Vuosikerta	219
DOI - pysyväislinkit	https://doi.org/10.1016/j.jpba.2022.114860
Tila	Julkaistu - 20 syysk. 2022
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

Pääsy asiakirjaan

10.1016/j.jpba.2022.114860

1-s2.0-S0731708522002813-mainLopullinen julkaistu versio, 2,32 MBLisenssi: CC BY

https://urn.fi/URN:NBN:fi-fe202301306376

Muut tiedostot ja linkit

View record in Web of Science

Viittausmuodot

Aarnio, R., Alzghool, OM., Wahlroos, S., O'Brien-Brown, J., Kassiou, M., Solin, O., Rinne, JO., Forsback, S., & Haaparanta-Solin, M. (2022). Novel plasma protein binding analysis method for a PET tracer and its radiometabolites: A case study with [C-11]SMW139 to explain the high uptake of radiometabolites in mouse brain. Journal of Pharmaceutical and Biomedical Analysis, 219, Artikkeli 114860. https://doi.org/10.1016/j.jpba.2022.114860

@article{fc46eba49d70483abce3a3a29354ccba,

title = "Novel plasma protein binding analysis method for a PET tracer and its radiometabolites: A case study with [C-11]SMW139 to explain the high uptake of radiometabolites in mouse brain",

keywords = "Parent fraction, Plasma protein binding, Positron emission tomography, RadioTLC, Radiometabolite analysis, Ultrafiltration, [C-11]SMW139",

author = "R Aarnio and OM Alzghool and S Wahlroos and J O'Brien-Brown and M Kassiou and O Solin and JO Rinne and S Forsback and M Haaparanta-Solin",

year = "2022",

month = sep,

day = "20",

doi = "10.1016/j.jpba.2022.114860",

language = "English",

volume = "219",

journal = "Journal of Pharmaceutical and Biomedical Analysis",

issn = "0731-7085",

publisher = "Elsevier",

}

Aarnio, R, Alzghool, OM, Wahlroos, S, O'Brien-Brown, J, Kassiou, M, Solin, O, Rinne, JO, Forsback, S & Haaparanta-Solin, M 2022, 'Novel plasma protein binding analysis method for a PET tracer and its radiometabolites: A case study with [C-11]SMW139 to explain the high uptake of radiometabolites in mouse brain', Journal of Pharmaceutical and Biomedical Analysis, Vuosikerta 219, 114860. https://doi.org/10.1016/j.jpba.2022.114860

Novel plasma protein binding analysis method for a PET tracer and its radiometabolites: A case study with [C-11]SMW139 to explain the high uptake of radiometabolites in mouse brain. / Aarnio, R; Alzghool, OM; Wahlroos, S et al.
julkaisussa: Journal of Pharmaceutical and Biomedical Analysis, Vuosikerta 219, 114860, 20.09.2022.

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - Novel plasma protein binding analysis method for a PET tracer and its radiometabolites

T2 - A case study with [C-11]SMW139 to explain the high uptake of radiometabolites in mouse brain

AU - Aarnio, R

AU - Alzghool, OM

AU - Wahlroos, S

AU - O'Brien-Brown, J

AU - Kassiou, M

AU - Solin, O

AU - Rinne, JO

AU - Forsback, S

AU - Haaparanta-Solin, M

PY - 2022/9/20

Y1 - 2022/9/20

KW - Parent fraction

KW - Plasma protein binding

KW - Positron emission tomography

KW - RadioTLC

KW - Radiometabolite analysis

KW - Ultrafiltration

KW - [C-11]SMW139

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=aboakademi&SrcAuth=WosAPI&KeyUT=WOS:000861996600008&DestLinkType=FullRecord&DestApp=WOS

U2 - 10.1016/j.jpba.2022.114860

DO - 10.1016/j.jpba.2022.114860

M3 - Article

C2 - 35738120

SN - 0731-7085

VL - 219

JO - Journal of Pharmaceutical and Biomedical Analysis

JF - Journal of Pharmaceutical and Biomedical Analysis

M1 - 114860

ER -