Mass spectrometric detection of nodularin and desmethylnodularin in mussels and flounders

Krister Karlsson; Vesa Sipiä; Harri Kankaanpää; Jussi Meriluoto

doi:10.1016/S1570-0232(02)00802-4

Mass spectrometric detection of nodularin and desmethylnodularin in mussels and flounders

Krister Karlsson
, Vesa Sipiä
, Harri Kankaanpää
, Jussi Meriluoto^*

^*Tämän työn vastaava kirjoittaja

Laboratoryservices

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

56 Sitaatiot (Scopus)

Abstrakti

Samples of mussels and flounders from the Baltic Sea were analysed for nodularin content on two different LC-MS instruments (triple quadrupole and ion trap). The triple quadrupole instrument was well suited for the quantitative analysis. The limit of detection in the selected ion recording mode was 5 pg and in the multiple reactant monitoring mode 500 pg on column for extracts of Nodularia spumigena. The fragmentation patterns of nodularin-R and desmethylnodularin-R were recorded and shown to be similar to those of microcystins. LC-MS proved to be an excellent tool for the analyses of cyanobacterial hepatotoxins in complex matrices.

Alkuperäiskieli	Englanti
Sivut	243-253
Sivumäärä	11
Julkaisu	Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
Vuosikerta	784
Numero	2
DOI - pysyväislinkit	https://doi.org/10.1016/S1570-0232(02)00802-4
Tila	Julkaistu - 5 helmik. 2003
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

Rahoitus

We wish to thank the Academy of Finland for financial support (RC for Natural Sciences and Engineering, project 47664 of J.M. and K.K., and RC for Biosciences and Environment, project 48019 of V.S.). K.K. also acknowledges the support from the National Graduate School of Informational and Structural Biology and the Magnus Ehrnrooth Foundation.

Pääsy asiakirjaan

10.1016/S1570-0232(02)00802-4

Muut tiedostot ja linkit

Linkki julkaisuun Scopuksessa

Viittausmuodot

@article{40dad8e343944c42bd5747cfbdeca92c,

title = "Mass spectrometric detection of nodularin and desmethylnodularin in mussels and flounders",

abstract = "Samples of mussels and flounders from the Baltic Sea were analysed for nodularin content on two different LC-MS instruments (triple quadrupole and ion trap). The triple quadrupole instrument was well suited for the quantitative analysis. The limit of detection in the selected ion recording mode was 5 pg and in the multiple reactant monitoring mode 500 pg on column for extracts of Nodularia spumigena. The fragmentation patterns of nodularin-R and desmethylnodularin-R were recorded and shown to be similar to those of microcystins. LC-MS proved to be an excellent tool for the analyses of cyanobacterial hepatotoxins in complex matrices.",

keywords = "Desmethylnodularin, Flounder, Mussel, Nodularin",

author = "Krister Karlsson and Vesa Sipi{\"a} and Harri Kankaanp{\"a}{\"a} and Jussi Meriluoto",

note = "Funding Information: We wish to thank the Academy of Finland for financial support (RC for Natural Sciences and Engineering, project 47664 of J.M. and K.K., and RC for Biosciences and Environment, project 48019 of V.S.). K.K. also acknowledges the support from the National Graduate School of Informational and Structural Biology and the Magnus Ehrnrooth Foundation. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

year = "2003",

month = feb,

day = "5",

doi = "10.1016/S1570-0232(02)00802-4",

language = "English",

volume = "784",

pages = "243--253",

journal = "Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences",

issn = "1570-0232",

publisher = "Elsevier",

number = "2",

}

Mass spectrometric detection of nodularin and desmethylnodularin in mussels and flounders. / Karlsson, Krister; Sipiä, Vesa; Kankaanpää, Harri et al.
julkaisussa: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Vuosikerta 784, Nro 2, 05.02.2003, s. 243-253.

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - Mass spectrometric detection of nodularin and desmethylnodularin in mussels and flounders

AU - Karlsson, Krister

AU - Sipiä, Vesa

AU - Kankaanpää, Harri

AU - Meriluoto, Jussi

N1 - Funding Information: We wish to thank the Academy of Finland for financial support (RC for Natural Sciences and Engineering, project 47664 of J.M. and K.K., and RC for Biosciences and Environment, project 48019 of V.S.). K.K. also acknowledges the support from the National Graduate School of Informational and Structural Biology and the Magnus Ehrnrooth Foundation. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2003/2/5

Y1 - 2003/2/5

N2 - Samples of mussels and flounders from the Baltic Sea were analysed for nodularin content on two different LC-MS instruments (triple quadrupole and ion trap). The triple quadrupole instrument was well suited for the quantitative analysis. The limit of detection in the selected ion recording mode was 5 pg and in the multiple reactant monitoring mode 500 pg on column for extracts of Nodularia spumigena. The fragmentation patterns of nodularin-R and desmethylnodularin-R were recorded and shown to be similar to those of microcystins. LC-MS proved to be an excellent tool for the analyses of cyanobacterial hepatotoxins in complex matrices.

AB - Samples of mussels and flounders from the Baltic Sea were analysed for nodularin content on two different LC-MS instruments (triple quadrupole and ion trap). The triple quadrupole instrument was well suited for the quantitative analysis. The limit of detection in the selected ion recording mode was 5 pg and in the multiple reactant monitoring mode 500 pg on column for extracts of Nodularia spumigena. The fragmentation patterns of nodularin-R and desmethylnodularin-R were recorded and shown to be similar to those of microcystins. LC-MS proved to be an excellent tool for the analyses of cyanobacterial hepatotoxins in complex matrices.

KW - Desmethylnodularin

KW - Flounder

KW - Mussel

KW - Nodularin

UR - https://www.scopus.com/pages/publications/0346036082

U2 - 10.1016/S1570-0232(02)00802-4

DO - 10.1016/S1570-0232(02)00802-4

M3 - Article

C2 - 12505772

AN - SCOPUS:0346036082

SN - 1570-0232

VL - 784

SP - 243

EP - 253

JO - Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

JF - Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

IS - 2

ER -

Mass spectrometric detection of nodularin and desmethylnodularin in mussels and flounders

Abstrakti

Rahoitus

Pääsy asiakirjaan

Muut tiedostot ja linkit

Sormenjälki

Viittausmuodot