Isomerization of bicyclic terpene epoxides into allylic alcohols without changing of the initial structure

Yulia Demidova, OV Ardashov, OA Simakova, Olga Simakova, KP Volcho, NF Salakhutdinov, Dmitry Murzin

    Tutkimustuotos: LehtiartikkeliArtikkeliTieteellinenvertaisarvioitu

    44 Sitaatiot (Scopus)

    Abstrakti

    A novel method of (1S,2R,3R,5R)-6,6-dimethy1-4-methylenebicyclo[3.1.1]heptane-2,3-diol synthesis, which is a valuable intermediate in the synthesis of a perspective potent anti-Parkinson drugs, in the presence of TiO2 was proposed. Catalytic activity of TiO2 in the bicyclic terpene epoxides isomerization to corresponding allylic alcohols without changing of the initial structure was demonstrated, contrary to titania-supported Au catalysts which promoted rearrangement with predominant formation of a cyclopentene alpha-hydroxy ketone.
    AlkuperäiskieliEi tiedossa
    Sivut162–166
    JulkaisuJournal of Molecular Catalysis A: Chemical
    Vuosikerta388-389
    DOI - pysyväislinkit
    TilaJulkaistu - 2014
    OKM-julkaisutyyppiA1 Julkaistu artikkeli, soviteltu

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