Influence of mass transfer on regio- and enantioselectivity in hydrogenation of 1-phenyl-1,2-propanedione over modified Pt catalysts

Esa Toukoniitty; Päivi Mäki-Arvela; Narendra Kumar; Tapio Salmi; Dmitry Yu Murzin

doi:10.1016/S0920-5861(03)00004-X

Influence of mass transfer on regio- and enantioselectivity in hydrogenation of 1-phenyl-1,2-propanedione over modified Pt catalysts

Esa Toukoniitty
, Päivi Mäki-Arvela
, Narendra Kumar
, Tapio Salmi
, Dmitry Yu Murzin^*

^*Tämän työn vastaava kirjoittaja

Teknillisen kemian ja reaktiotekniikan laboratorio

Tutkimustuotos: Lehtiartikkeli › Konferenssiartikkeli › Tieteellinen › vertaisarvioitu

11 Sitaatiot (Scopus)

Abstrakti

The influence of mass transfer limitations on the enantio- and regioselectivity in hydrogenation of 1-phenyl-1,2-propanedione was studied. Gas-liquid mass transfer limitation as well as liquid-solid mass transfer limitation did not influence the enantio- and regioselectivity of the reaction, compared to the performance of the system under kinetic control. Under various regimes, the enantiomeric excess of the (R)-1-hydroxy-1-phenylpropanone was about 55% and regioselectivity remained at about 10, which makes process scale-up with respect to enantio- and regioselectivity straightforward.

Alkuperäiskieli	Englanti
Sivut	189-193
Sivumäärä	5
Julkaisu	Catalysis Today
Vuosikerta	79-80
DOI - pysyväislinkit	https://doi.org/10.1016/S0920-5861(03)00004-X
Tila	Julkaistu - 30 huhtik. 2003
OKM-julkaisutyyppi	A4 Artikkeli konferenssijulkaisuussa
Tapahtuma	Catalysis in Multiphase Reactors - Naples, Italy Kesto: 29 toukok. 2000 → 29 toukok. 2000

Rahoitus

This work is part of the activities at the Åbo Akademi Process Chemistry Group within the Finnish Centre of Excellence Programme (2000–2005) by the Academy of Finland. Financial support from Finnish Graduate School in Chemical Engineering (GSCE) is gratefully acknowledged.

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10.1016/S0920-5861(03)00004-X

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@article{5d826b72e9d94e5f97430945a3cb7af9,

title = "Influence of mass transfer on regio- and enantioselectivity in hydrogenation of 1-phenyl-1,2-propanedione over modified Pt catalysts",

abstract = "The influence of mass transfer limitations on the enantio- and regioselectivity in hydrogenation of 1-phenyl-1,2-propanedione was studied. Gas-liquid mass transfer limitation as well as liquid-solid mass transfer limitation did not influence the enantio- and regioselectivity of the reaction, compared to the performance of the system under kinetic control. Under various regimes, the enantiomeric excess of the (R)-1-hydroxy-1-phenylpropanone was about 55\% and regioselectivity remained at about 10, which makes process scale-up with respect to enantio- and regioselectivity straightforward.",

keywords = "1-Phenyl-1,2-propanedione, Mass transfer, Pt catalysts",

author = "Esa Toukoniitty and P{\"a}ivi M{\"a}ki-Arvela and Narendra Kumar and Tapio Salmi and Murzin, \{Dmitry Yu\}",

note = "Funding Information: This work is part of the activities at the {\AA}bo Akademi Process Chemistry Group within the Finnish Centre of Excellence Programme (2000–2005) by the Academy of Finland. Financial support from Finnish Graduate School in Chemical Engineering (GSCE) is gratefully acknowledged. Copyright: Copyright 2004 Elsevier Science B.V., Amsterdam. All rights reserved.; Catalysis in Multiphase Reactors ; Conference date: 29-05-2000 Through 29-05-2000",

year = "2003",

month = apr,

day = "30",

doi = "10.1016/S0920-5861(03)00004-X",

language = "English",

volume = "79-80",

pages = "189--193",

journal = "Catalysis Today",

issn = "0920-5861",

publisher = "Elsevier",

}

TY - JOUR

T1 - Influence of mass transfer on regio- and enantioselectivity in hydrogenation of 1-phenyl-1,2-propanedione over modified Pt catalysts

AU - Toukoniitty, Esa

AU - Mäki-Arvela, Päivi

AU - Kumar, Narendra

AU - Salmi, Tapio

AU - Murzin, Dmitry Yu

N1 - Funding Information: This work is part of the activities at the Åbo Akademi Process Chemistry Group within the Finnish Centre of Excellence Programme (2000–2005) by the Academy of Finland. Financial support from Finnish Graduate School in Chemical Engineering (GSCE) is gratefully acknowledged. Copyright: Copyright 2004 Elsevier Science B.V., Amsterdam. All rights reserved.

PY - 2003/4/30

Y1 - 2003/4/30

N2 - The influence of mass transfer limitations on the enantio- and regioselectivity in hydrogenation of 1-phenyl-1,2-propanedione was studied. Gas-liquid mass transfer limitation as well as liquid-solid mass transfer limitation did not influence the enantio- and regioselectivity of the reaction, compared to the performance of the system under kinetic control. Under various regimes, the enantiomeric excess of the (R)-1-hydroxy-1-phenylpropanone was about 55% and regioselectivity remained at about 10, which makes process scale-up with respect to enantio- and regioselectivity straightforward.

AB - The influence of mass transfer limitations on the enantio- and regioselectivity in hydrogenation of 1-phenyl-1,2-propanedione was studied. Gas-liquid mass transfer limitation as well as liquid-solid mass transfer limitation did not influence the enantio- and regioselectivity of the reaction, compared to the performance of the system under kinetic control. Under various regimes, the enantiomeric excess of the (R)-1-hydroxy-1-phenylpropanone was about 55% and regioselectivity remained at about 10, which makes process scale-up with respect to enantio- and regioselectivity straightforward.

KW - 1-Phenyl-1,2-propanedione

KW - Mass transfer

KW - Pt catalysts

UR - https://www.scopus.com/pages/publications/0038558317

U2 - 10.1016/S0920-5861(03)00004-X

DO - 10.1016/S0920-5861(03)00004-X

M3 - Conference article

AN - SCOPUS:0038558317

SN - 0920-5861

VL - 79-80

SP - 189

EP - 193

JO - Catalysis Today

JF - Catalysis Today

T2 - Catalysis in Multiphase Reactors

Y2 - 29 May 2000 through 29 May 2000

ER -

Influence of mass transfer on regio- and enantioselectivity in hydrogenation of 1-phenyl-1,2-propanedione over modified Pt catalysts

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