In vitro behavior of yttrium silica sol-gel microspheres

D Cacaina, R Viitala, M Jokinen, H Ylanen, Mikko Hupa, S Simon

    Tutkimustuotos: LehtiartikkeliArtikkeliTieteellinenvertaisarvioitu

    8 Sitaatiot (Scopus)

    Abstrakti

    Biodegradable silica microspheres containing neutron activable yttrium cations were investigated as a potential material for in situ radiotherapy of cancers. The sol-gel method used for preparing the microspheres allows obtaining at relative low temperatures materials of high purity and homogeneity, with controlled rate of biodegradability. The influence of yttrium on the biodegradability of the silica microspheres was studied in a simulated body fluid (SBF). The chemical durability of the microspheres was investigated under in vitro conditions and the concentration of yttrium released from the microspheres was determined.
    AlkuperäiskieliEi tiedossa
    Sivut411–414
    Sivumäärä4
    JulkaisuKey Engineering Materials
    Vuosikerta284-286
    DOI - pysyväislinkit
    TilaJulkaistu - 2005
    OKM-julkaisutyyppiA1 Julkaistu artikkeli, soviteltu

    Keywords

    • bioactive glasses
    • release behaviour
    • SBF
    • sol gel
    • yttrium

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