Abstrakti
Liquid chromatography-electrospray ionisation mass spectrometry was evaluated in the high-throughput analysis of microcystins and nodularins, cyanobacterial peptide hepatotoxins. Extracts originating from cyanobacterial strains and field material were separated on a 30 mm x 4 mm I.D. Merck Purospher STAR RP-18e column using a rapid gradient of aqueous formic acid and acetonitrile, ionised by electrospray technique and analysed on a Micromass Quattro II triple-quadrupole mass spectrometer operated in the selected ion recording (SIR) mode. The total analysis time per sample was 2.8 min corresponding to 514 samples a day. The system showed good robustness during a series of 320 repetitive injections of a field sample containing three major microcystins.
Alkuperäiskieli | Englanti |
---|---|
Sivut | 291-298 |
Sivumäärä | 8 |
Julkaisu | Chromatographia |
Vuosikerta | 59 |
Numero | 5-6 |
Tila | Julkaistu - maalisk. 2004 |
OKM-julkaisutyyppi | A1 Julkaistu artikkeli, soviteltu |