High specific activity Cu-61 via Zn-64(p,α)Cu-61 reaction at low proton energies

Stefan Thieme; Martin Walther; Stephan Preusche; Johan Rajander; Hans-Jürgen Pietzsch; Jan-Olof Lill; Michael Kaden; Olof Solin; Jörg Steinbach

doi:10.1016/j.apradiso.2012.11.007

High specific activity Cu-61 via Zn-64(p,α)Cu-61 reaction at low proton energies

Stefan Thieme
, Martin Walther
, Stephan Preusche
, Johan Rajander
, Hans-Jürgen Pietzsch
, Jan-Olof Lill
, Michael Kaden
, Olof Solin
, Jörg Steinbach

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

24 Sitaatiot (Scopus)

Abstrakti

The PET radionuclide Cu-61 is accessible through several nuclear reactions. Besides the common production route via Ni-61(p,n)Cu-61 the Zn-64(p,alpha)Cu-61 reaction offers some advantages. Especially the comparatively cheap enriched Zn-64 makes this process economical. For fast product purification and recycling of target material an ion exchange cascade was developed. In addition a separation technique with a copper selective resin was tested. Cu-61 with specific activities up to 1000 GBq/mu mol was produced with these methods. (c) 2012 Elsevier Ltd. All rights reserved.

Alkuperäiskieli	Ei tiedossa
Sivut	169–176
Sivumäärä	8
Julkaisu	Applied Radiation and Isotopes
Vuosikerta	72
DOI - pysyväislinkit	https://doi.org/10.1016/j.apradiso.2012.11.007
Tila	Julkaistu - 2013
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

Keywords

Cu-61
Cyclotron
PET imaging
Targetry
Zn-64

Pääsy asiakirjaan

10.1016/j.apradiso.2012.11.007

Viittausmuodot

@article{57a52ed2e15545cb9c5cd3611045dcbc,

title = "High specific activity Cu-61 via Zn-64(p,α)Cu-61 reaction at low proton energies",

abstract = "The PET radionuclide Cu-61 is accessible through several nuclear reactions. Besides the common production route via Ni-61(p,n)Cu-61 the Zn-64(p,alpha)Cu-61 reaction offers some advantages. Especially the comparatively cheap enriched Zn-64 makes this process economical. For fast product purification and recycling of target material an ion exchange cascade was developed. In addition a separation technique with a copper selective resin was tested. Cu-61 with specific activities up to 1000 GBq/mu mol was produced with these methods. (c) 2012 Elsevier Ltd. All rights reserved.",

keywords = "Cu-61, Cyclotron, PET imaging, Targetry, Zn-64, Cu-61, Cyclotron, PET imaging, Targetry, Zn-64, Cu-61, Cyclotron, PET imaging, Targetry, Zn-64",

author = "Stefan Thieme and Martin Walther and Stephan Preusche and Johan Rajander and Hans-J{\"u}rgen Pietzsch and Jan-Olof Lill and Michael Kaden and Olof Solin and J{\"o}rg Steinbach",

year = "2013",

doi = "10.1016/j.apradiso.2012.11.007",

language = "Odefinierat/ok{\"a}nt",

volume = "72",

pages = "169–176",

journal = "Applied Radiation and Isotopes",

issn = "0969-8043",

publisher = "Elsevier",

}

TY - JOUR

T1 - High specific activity Cu-61 via Zn-64(p,α)Cu-61 reaction at low proton energies

AU - Thieme, Stefan

AU - Walther, Martin

AU - Preusche, Stephan

AU - Rajander, Johan

AU - Pietzsch, Hans-Jürgen

AU - Lill, Jan-Olof

AU - Kaden, Michael

AU - Solin, Olof

AU - Steinbach, Jörg

PY - 2013

Y1 - 2013

N2 - The PET radionuclide Cu-61 is accessible through several nuclear reactions. Besides the common production route via Ni-61(p,n)Cu-61 the Zn-64(p,alpha)Cu-61 reaction offers some advantages. Especially the comparatively cheap enriched Zn-64 makes this process economical. For fast product purification and recycling of target material an ion exchange cascade was developed. In addition a separation technique with a copper selective resin was tested. Cu-61 with specific activities up to 1000 GBq/mu mol was produced with these methods. (c) 2012 Elsevier Ltd. All rights reserved.

AB - The PET radionuclide Cu-61 is accessible through several nuclear reactions. Besides the common production route via Ni-61(p,n)Cu-61 the Zn-64(p,alpha)Cu-61 reaction offers some advantages. Especially the comparatively cheap enriched Zn-64 makes this process economical. For fast product purification and recycling of target material an ion exchange cascade was developed. In addition a separation technique with a copper selective resin was tested. Cu-61 with specific activities up to 1000 GBq/mu mol was produced with these methods. (c) 2012 Elsevier Ltd. All rights reserved.

KW - Cu-61

KW - Cyclotron

KW - PET imaging

KW - Targetry

KW - Zn-64

KW - Cu-61

KW - Cyclotron

KW - PET imaging

KW - Targetry

KW - Zn-64

KW - Cu-61

KW - Cyclotron

KW - PET imaging

KW - Targetry

KW - Zn-64

U2 - 10.1016/j.apradiso.2012.11.007

DO - 10.1016/j.apradiso.2012.11.007

M3 - Artikel

SN - 0969-8043

VL - 72

SP - 169

EP - 176

JO - Applied Radiation and Isotopes

JF - Applied Radiation and Isotopes

ER -