In this article, we analyse Google trends of Industry 4.0 technologies and key concepts. This study provides global landscape analysis of Industry 4.0 technologies and two key concepts, digital transformation and business transformation in years 2004–2021. The study reports key trends of Google Trends database. To understand (1) the importance of key technology trends and (2) interactions of key Industry 4.0 trends, empirical Big Data study reports correlation analysis and ranking analyses of Industry 4.0 technologies for years 2005, 2010, 2015 and 2021. The study covers nine technology domains of Industry 4.0 technologies: Big Data and AI analytics, Horizontal and Vertical Integration, Cloud computing, Augmented and Virtual Reality (AR-VR), Industrial Internet of Things (IIoT), (6) Additive manufacturing/3D/4D printing, Robotics, Autonomous robots or/and collaborative robots, Simulation/digital twins, Cybersecurity and Blockchain technology.