Global SUMOylation on active chromatin is an acute heat stress response restricting transcription

EA Niskanen; M Malinen; P Sutinen; S Toropainen; V Paakinaho; Johanna Vihervaara; Jenny Joutsen; MU Kaikkonen; Lea Sistonen; JJ Palvimo

doi:10.1186/s13059-015-0717-y

Global SUMOylation on active chromatin is an acute heat stress response restricting transcription

EA Niskanen, M Malinen, P Sutinen, S Toropainen, V Paakinaho, Johanna Vihervaara, Jenny Joutsen, MU Kaikkonen, Lea Sistonen, JJ Palvimo

Cell Biology

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

59 Sitaatiot (Scopus)

Abstrakti

Conclusions: HS-triggered SUMOylation targets promoters and enhancers of actively transcribed genes where it restricts the transcriptional activity of the HS-induced genes. PIAS1-mediated promoter SUMOylation is likely to regulate Pol2-associated factors in HS.

Alkuperäiskieli	Ei tiedossa
Sivut	1–19
Sivumäärä	19
Julkaisu	GENOME BIOLOGY
Vuosikerta	16
DOI - pysyväislinkit	https://doi.org/10.1186/s13059-015-0717-y
Tila	Julkaistu - 2015
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

Pääsy asiakirjaan

10.1186/s13059-015-0717-y

Viittausmuodot

@article{a642e17b5a854734ab1c3ae4afad1ef8,

title = "Global SUMOylation on active chromatin is an acute heat stress response restricting transcription",

abstract = "Conclusions: HS-triggered SUMOylation targets promoters and enhancers of actively transcribed genes where it restricts the transcriptional activity of the HS-induced genes. PIAS1-mediated promoter SUMOylation is likely to regulate Pol2-associated factors in HS.",

author = "EA Niskanen and M Malinen and P Sutinen and S Toropainen and V Paakinaho and Johanna Vihervaara and Jenny Joutsen and MU Kaikkonen and Lea Sistonen and JJ Palvimo",

year = "2015",

doi = "10.1186/s13059-015-0717-y",

language = "Odefinierat/ok{\"a}nt",

volume = "16",

pages = "1–19",

journal = "GENOME BIOLOGY",

issn = "1474-7596",

publisher = "Biomed central",

}

Global SUMOylation on active chromatin is an acute heat stress response restricting transcription. / Niskanen, EA; Malinen, M; Sutinen, P; Toropainen, S; Paakinaho, V; Vihervaara, Johanna; Joutsen, Jenny; Kaikkonen, MU; Sistonen, Lea; Palvimo, JJ.

julkaisussa: GENOME BIOLOGY, Vuosikerta 16, 2015, s. 1–19.

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - Global SUMOylation on active chromatin is an acute heat stress response restricting transcription

AU - Niskanen, EA

AU - Malinen, M

AU - Sutinen, P

AU - Toropainen, S

AU - Paakinaho, V

AU - Vihervaara, Johanna

AU - Joutsen, Jenny

AU - Kaikkonen, MU

AU - Sistonen, Lea

AU - Palvimo, JJ

PY - 2015

Y1 - 2015

N2 - Conclusions: HS-triggered SUMOylation targets promoters and enhancers of actively transcribed genes where it restricts the transcriptional activity of the HS-induced genes. PIAS1-mediated promoter SUMOylation is likely to regulate Pol2-associated factors in HS.

AB - Conclusions: HS-triggered SUMOylation targets promoters and enhancers of actively transcribed genes where it restricts the transcriptional activity of the HS-induced genes. PIAS1-mediated promoter SUMOylation is likely to regulate Pol2-associated factors in HS.

U2 - 10.1186/s13059-015-0717-y

DO - 10.1186/s13059-015-0717-y

M3 - Artikel

VL - 16

SP - 1

EP - 19

JO - GENOME BIOLOGY

JF - GENOME BIOLOGY

SN - 1474-7596

ER -