Evolving Technologies and Strategies for Combating Antibacterial Resistance in the Advent of the Postantibiotic Era

Didem Sen Karaman, Utku Kürşat Ercan, Emel Bakay, Nermin Topaloğlu, Jessica Rosenholm

Tutkimustuotos: LehtiartikkeliArtikkeliTieteellinenvertaisarvioitu

12 Sitaatiot (Scopus)
33 Lataukset (Pure)

Abstrakti

The threats posed by the impending “postantibiotic era” have put forward urgent challenges to be overcome by providing new diagnostic and therapeutic regimes for improved diagnosis and treatment of bacterial infections. Antibiotic resistance and incurable bacterial infections are especially important in a society faced with rapid demographic changes. With very few new antibiotics in the drug development pipeline, not being able to match the pace of antimicrobial resistance evolution, developments within other fields such as materials sciences and medical technologies are required to realize innovative antibacterial approaches. This progress report presents recent advances in especially nanotechnology-based approaches and their concomitant use with complementary antibacterial treatments. Synergistically improved antibacterial activity can be reached by considering novel, promising approaches such as photodynamic and photothermal therapy as well as cold atmospheric pressure treatments as complementary strategies to fight against antibacterial resistance. Moreover, this report describes how these novel technologies can be further improved especially by integration of nanomaterials into the currently applied single modal strategies against bacterial infections.
AlkuperäiskieliEnglanti
Artikkeli1908783
Sivut
JulkaisuAdvanced Functional Materials
Vuosikerta30
Numero15
DOI - pysyväislinkit
TilaJulkaistu - 13 helmikuuta 2020
OKM-julkaisutyyppiA1 Julkaistu artikkeli, soviteltu

Keywords

  • antibiotic resistance
  • Antimicrobial resistance (AMR)

Sormenjälki

Sukella tutkimusaiheisiin 'Evolving Technologies and Strategies for Combating Antibacterial Resistance in the Advent of the Postantibiotic Era'. Ne muodostavat yhdessä ainutlaatuisen sormenjäljen.

Viittausmuodot