Electronic biosensors based on EGOFETs

Mohammad Y. Mulla, Luisa Torsi, Kyriaki Manoli

Tutkimustuotos: Artikkeli kirjassa/raportissa/konferenssijulkaisussaLukuTieteellinenvertaisarvioitu

Abstrakti

There is an increasing interest for low cost, ultrasensitive, time saving yet reliable, point-of-care bioelectronic sensors. Electrolyte gated organic field effect transistors (EGOFETs) are proven compelling transducers for various sensing applications, offering direct electronic, label-free transduction of bio-recognition events along with miniaturization, fast data handling and processing. Given that field effect transistors act as intrinsically signal amplifiers, even a small change of a chemical or biological quantity may significantly alter the output electronic signal. In EGOFETs selectivity can be guaranteed by the immobilization of bioreceptors able to bind specifically a target analyte. The layer of receptors can be linked to one of the electronic active interfaces of the transistor, and the interactions with a target molecule affect the electronic properties of the device. The present chapter discusses main aspects of EGOFETs transducers along with detailed examples of how to tailor the device interfaces with desired functionality. The development of an “electronic tongue” based on an EGOFET device coupled to odorant binding proteins (OBPs) for enantiomers differentiation is presented.
AlkuperäiskieliEnglanti
OtsikkoOdorant Binding and Chemosensory Proteins
ToimittajatPaolo Pelosi, Wolfgang Knoll
KustantajaElsevier
Luku17
Sivut403-433
Sivumäärä31
Vuosikerta642
ISBN (painettu)978-0-12-821157-1
DOI - pysyväislinkit
TilaJulkaistu - 2020
OKM-julkaisutyyppiA3 Kirjan osa tai toinen tutkimuskirja

Julkaisusarja

NimiMethods in Enzymology
KustantajaElsevier
ISSN (painettu)0076-6879

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