Electrochemical detection of homovanillic acid, a breast cancer biomarker, using Pluronic-modified MoS2nanosheets

Mohammed Zniber; Parastoo Vahdatiyekta; Shounak Roy; Kostiantyn Nikiforow; Amit Jaiswal; Tan-Phat Huynh

doi:10.1088/2399-1984/ac8215

Electrochemical detection of homovanillic acid, a breast cancer biomarker, using Pluronic-modified MoS₂nanosheets

Mohammed Zniber, Parastoo Vahdatiyekta, Shounak Roy, Kostiantyn Nikiforow, Amit Jaiswal^*, Tan-Phat Huynh^*

^*Tämän työn vastaava kirjoittaja

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

7 Sitaatiot (Scopus)

56 Lataukset (Pure)

Abstrakti

Two-dimensional transition metal dichalcogenides have gained considerable attention from the scientific community for their various applications thanks to their remarkable chemical, physical, optical and electronic properties. In this study, MoS2 nanosheets were synthesized using a kitchen blender with the assistance of a surfactant, Pluronic F-127, through a shear-exfoliation process. The chemical composition, nanostructure and electrochemical properties of the synthesized MoS2-F127 were characterized by different methods. A Pt electrode modified with MoS2-F127 (Pt/MoS2-F127) was used with differential pulse voltammetry for the electrochemical detection of homovanillic acid (HVA) - a breast-cancer biomarker, in the presence of common interferents in urine. This study provides a new approach to discriminate the electrochemical signals of HVA and uric acid, leading to higher selectivity of the sensor.

Alkuperäiskieli	Englanti
Artikkeli	035002
Julkaisu	Nano Futures
Vuosikerta	6
Numero	3
DOI - pysyväislinkit	https://doi.org/10.1088/2399-1984/ac8215
Tila	Julkaistu - 26 elok. 2022
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

Pääsy asiakirjaan

10.1088/2399-1984/ac8215Lisenssi: All rights reserved

MoS2-F127 manuscript - revised #2 clean versionHyväksytty kirjoittajan käsikirjoitus, 2,23 MBLisenssi: CC BY-NC-ND

https://urn.fi/URN:NBN:fi-fe20230901115091

Muut tiedostot ja linkit

Linkki julkaisuun Scopuksessa

FICORE: Finnish Indian Collaboration in Research and Education
Henelius, P. (Vastuullinen tutkija), Österbacka, R. (CoPI), De Blasio, C. (CoI), Salo-Ahen, O. (CoI), Huynh, T. P. (CoI), Yrjas, P. (CoI) & Saxén, H. (CoI)
Opetus- ja kulttuuriministeriö
01/01/21 → 31/12/24
Projekti: Ministry / Government Agency

Viittausmuodot

@article{d0a52aa6605641f48cd497625e666af5,

title = "Electrochemical detection of homovanillic acid, a breast cancer biomarker, using Pluronic-modified MoS2nanosheets",

abstract = "Two-dimensional transition metal dichalcogenides have gained considerable attention from the scientific community for their various applications thanks to their remarkable chemical, physical, optical and electronic properties. In this study, MoS2 nanosheets were synthesized using a kitchen blender with the assistance of a surfactant, Pluronic F-127, through a shear-exfoliation process. The chemical composition, nanostructure and electrochemical properties of the synthesized MoS2-F127 were characterized by different methods. A Pt electrode modified with MoS2-F127 (Pt/MoS2-F127) was used with differential pulse voltammetry for the electrochemical detection of homovanillic acid (HVA) - a breast-cancer biomarker, in the presence of common interferents in urine. This study provides a new approach to discriminate the electrochemical signals of HVA and uric acid, leading to higher selectivity of the sensor.",

keywords = "breast cancer, electrochemical, homovanillic acid, sensor, urine",

author = "Mohammed Zniber and Parastoo Vahdatiyekta and Shounak Roy and Kostiantyn Nikiforow and Amit Jaiswal and Tan-Phat Huynh",

note = "Funding Information: T-P H acknowledges the Liv och H{\"a}lsa Foundation and the Academy of Finland (Grant Nos. 323240 and 331774) for financial support. All authors acknowledge the INDFICORE (Indian Finnish Consortia for Research and Education). A J acknowledges the support from BioX centre and Advanced Materials Research Centre (AMRC), Indian Institute of Technology Mandi for research and infrastructure facility. Publisher Copyright: {\textcopyright} 2022 IOP Publishing Ltd.",

year = "2022",

month = aug,

day = "26",

doi = "10.1088/2399-1984/ac8215",

language = "English",

volume = "6",

journal = "Nano Futures",

issn = "2399-1984",

publisher = "IOP Publishing",

number = "3",

}

TY - JOUR

T1 - Electrochemical detection of homovanillic acid, a breast cancer biomarker, using Pluronic-modified MoS2nanosheets

AU - Zniber, Mohammed

AU - Vahdatiyekta, Parastoo

AU - Roy, Shounak

AU - Nikiforow, Kostiantyn

AU - Jaiswal, Amit

AU - Huynh, Tan-Phat

N1 - Funding Information: T-P H acknowledges the Liv och Hälsa Foundation and the Academy of Finland (Grant Nos. 323240 and 331774) for financial support. All authors acknowledge the INDFICORE (Indian Finnish Consortia for Research and Education). A J acknowledges the support from BioX centre and Advanced Materials Research Centre (AMRC), Indian Institute of Technology Mandi for research and infrastructure facility. Publisher Copyright: © 2022 IOP Publishing Ltd.

PY - 2022/8/26

Y1 - 2022/8/26

N2 - Two-dimensional transition metal dichalcogenides have gained considerable attention from the scientific community for their various applications thanks to their remarkable chemical, physical, optical and electronic properties. In this study, MoS2 nanosheets were synthesized using a kitchen blender with the assistance of a surfactant, Pluronic F-127, through a shear-exfoliation process. The chemical composition, nanostructure and electrochemical properties of the synthesized MoS2-F127 were characterized by different methods. A Pt electrode modified with MoS2-F127 (Pt/MoS2-F127) was used with differential pulse voltammetry for the electrochemical detection of homovanillic acid (HVA) - a breast-cancer biomarker, in the presence of common interferents in urine. This study provides a new approach to discriminate the electrochemical signals of HVA and uric acid, leading to higher selectivity of the sensor.

AB - Two-dimensional transition metal dichalcogenides have gained considerable attention from the scientific community for their various applications thanks to their remarkable chemical, physical, optical and electronic properties. In this study, MoS2 nanosheets were synthesized using a kitchen blender with the assistance of a surfactant, Pluronic F-127, through a shear-exfoliation process. The chemical composition, nanostructure and electrochemical properties of the synthesized MoS2-F127 were characterized by different methods. A Pt electrode modified with MoS2-F127 (Pt/MoS2-F127) was used with differential pulse voltammetry for the electrochemical detection of homovanillic acid (HVA) - a breast-cancer biomarker, in the presence of common interferents in urine. This study provides a new approach to discriminate the electrochemical signals of HVA and uric acid, leading to higher selectivity of the sensor.

KW - breast cancer

KW - electrochemical

KW - homovanillic acid

KW - sensor

KW - urine

UR - http://www.scopus.com/inward/record.url?scp=85137266159&partnerID=8YFLogxK

U2 - 10.1088/2399-1984/ac8215

DO - 10.1088/2399-1984/ac8215

M3 - Article

AN - SCOPUS:85137266159

SN - 2399-1984

VL - 6

JO - Nano Futures

JF - Nano Futures

IS - 3

M1 - 035002

ER -

Electrochemical detection of homovanillic acid, a breast cancer biomarker, using Pluronic-modified MoS2nanosheets

Abstrakti

Pääsy asiakirjaan

Muut tiedostot ja linkit

Sormenjälki

Projektit

FICORE: Finnish Indian Collaboration in Research and Education

Viittausmuodot

Electrochemical detection of homovanillic acid, a breast cancer biomarker, using Pluronic-modified MoS₂nanosheets