Dual functional construct containing kartogenin releasing microtissues and curcumin for cartilage regeneration

Negin Asgari; Fatemeh Bagheri; Mohamadreza Baghaban Eslaminejad; Mohammad Hossein Ghanian; Forogh Azam Sayahpour; Amir Mohammad Ghafari

doi:10.1186/s13287-020-01797-2

Dual functional construct containing kartogenin releasing microtissues and curcumin for cartilage regeneration

Negin Asgari
, Fatemeh Bagheri
, Mohamadreza Baghaban Eslaminejad
, Mohammad Hossein Ghanian
, Forogh Azam Sayahpour
, Amir Mohammad Ghafari

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

41 Sitaatiot (Scopus)

139 Lataukset (Pure)

Abstrakti

Regeneration of articular cartilage poses a tremendous challenge due to its limited self-repair capability and inflammation at the damaged site. To generate the desired structures that mimic the structure of native tissue, microtissues with repeated functional units such as cell aggregates have been developed. Multicellular aggregates of mesenchymal stem cells (MSCs) can be used as microscale building blocks of cartilage due to their potential for cell-cell contact, cell proliferation, and differentiation.

Alkuperäiskieli	Englanti
Artikkeli	289
Julkaisu	Stem Cell Research & Therapy
Vuosikerta	11
Numero	1
DOI - pysyväislinkit	https://doi.org/10.1186/s13287-020-01797-2
Tila	Julkaistu - 16 heinäk. 2020
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

Pääsy asiakirjaan

10.1186/s13287-020-01797-2Lisenssi: CC BY

s13287-020-01797-2Lopullinen julkaistu versio, 2,5 MBLisenssi: CC BY

https://urn.fi/URN:NBN:fi-fe202201148207

Viittausmuodot

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abstract = "Regeneration of articular cartilage poses a tremendous challenge due to its limited self-repair capability and inflammation at the damaged site. To generate the desired structures that mimic the structure of native tissue, microtissues with repeated functional units such as cell aggregates have been developed. Multicellular aggregates of mesenchymal stem cells (MSCs) can be used as microscale building blocks of cartilage due to their potential for cell-cell contact, cell proliferation, and differentiation.",

author = "Negin Asgari and Fatemeh Bagheri and Eslaminejad, \{Mohamadreza Baghaban\} and Ghanian, \{Mohammad Hossein\} and Sayahpour, \{Forogh Azam\} and Ghafari, \{Amir Mohammad\}",

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T1 - Dual functional construct containing kartogenin releasing microtissues and curcumin for cartilage regeneration

AU - Asgari, Negin

AU - Bagheri, Fatemeh

AU - Eslaminejad, Mohamadreza Baghaban

AU - Ghanian, Mohammad Hossein

AU - Sayahpour, Forogh Azam

AU - Ghafari, Amir Mohammad

PY - 2020/7/16

Y1 - 2020/7/16

N2 - Regeneration of articular cartilage poses a tremendous challenge due to its limited self-repair capability and inflammation at the damaged site. To generate the desired structures that mimic the structure of native tissue, microtissues with repeated functional units such as cell aggregates have been developed. Multicellular aggregates of mesenchymal stem cells (MSCs) can be used as microscale building blocks of cartilage due to their potential for cell-cell contact, cell proliferation, and differentiation.

AB - Regeneration of articular cartilage poses a tremendous challenge due to its limited self-repair capability and inflammation at the damaged site. To generate the desired structures that mimic the structure of native tissue, microtissues with repeated functional units such as cell aggregates have been developed. Multicellular aggregates of mesenchymal stem cells (MSCs) can be used as microscale building blocks of cartilage due to their potential for cell-cell contact, cell proliferation, and differentiation.

U2 - 10.1186/s13287-020-01797-2

DO - 10.1186/s13287-020-01797-2

M3 - Article

SN - 1757-6512

VL - 11

JO - Stem Cell Research & Therapy

JF - Stem Cell Research & Therapy

IS - 1

M1 - 289

ER -

Dual functional construct containing kartogenin releasing microtissues and curcumin for cartilage regeneration

Abstrakti

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