Dicarbonylchloro(pentabenzylcyclopentadienyl)ruthenium as Racemization Catalyst in the Dynamic Kinetic Resolution of Secondary Alcohols

D Mavrynsky, M Paivio, K Lundell, R Sillanpaa, LT Kanerva, Reko Leino

    Tutkimustuotos: LehtiartikkeliArtikkeliTieteellinenvertaisarvioitu

    29 Sitaatiot (Scopus)

    Abstrakti

    Dicarbonylchloro(pentabenzylcyclopentadienyl)ruthenium has been prepared and its structure confirmed by X-ray analysis, This complex shows excellent catalytic activity and modest stability against air in racemization reactions of secondary alcohols. In Candida antarctica lipase B (CAL-B) catalyzed dynamic kinetic resolution (DKR) of 1-phenyl- and 1-(furan-2-yl)ethanol compounds, the new complex shows improved performance as an alcohol racemization catalyst in comparison with its well-known pentaphenylcyclopentadienyl analogue, hitherto considered as the leading catalyst candidate. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
    AlkuperäiskieliEi tiedossa
    Sivut1317–1320
    Sivumäärä4
    JulkaisuEuropean Journal of Organic Chemistry
    Vuosikerta2009
    Numero9
    DOI - pysyväislinkit
    TilaJulkaistu - 2009
    OKM-julkaisutyyppiA1 Julkaistu artikkeli, soviteltu

    Keywords

    • Cyclopentadienyl ligands
    • Dynamic kinetic resolution
    • Enzyme catalysis
    • Racemization
    • Ruthenium

    Viittausmuodot