Continuous enantioselective hydrogenation of ethylbenzoylformate over Pt/Al2O3 catalyst: Bed dilution effects and cinchonidine adsorption study

E. Toukoniitty; P. Mäki-Arvela; N. Kumar; T. Salmi; D. Yu Murzin

doi:10.1023/B:CATL.0000027292.23132.5c

Continuous enantioselective hydrogenation of ethylbenzoylformate over Pt/Al₂O₃ catalyst: Bed dilution effects and cinchonidine adsorption study

E. Toukoniitty, P. Mäki-Arvela, N. Kumar, T. Salmi, D. Yu Murzin^*

^*Tämän työn vastaava kirjoittaja

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

28 Sitaatiot (Scopus)

Abstrakti

Depending on the reaction medium (toluene or acetic acid) striking differences were observed in the development of enantiomeric excess with time-on-stream in continuous enantioselective hydrogenation of ethylbenzoylformate on cinchonidine-modified Pt/Al₂O₃, which correlated well with the amount of adsorbed cinchonidine on alumina and silica from acetic acid and toluene solutions. Maximally 93% enantiometric excess (ee) of (R)-ethyl mandelate was obtained.

Alkuperäiskieli	Englanti
Sivut	179-183
Sivumäärä	5
Julkaisu	Catalysis Letters
Vuosikerta	95
Numero	3-4
DOI - pysyväislinkit	https://doi.org/10.1023/B:CATL.0000027292.23132.5c
Tila	Julkaistu - kesäk. 2004
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

Pääsy asiakirjaan

10.1023/B:CATL.0000027292.23132.5c

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title = "Continuous enantioselective hydrogenation of ethylbenzoylformate over Pt/Al2O3 catalyst: Bed dilution effects and cinchonidine adsorption study",

abstract = "Depending on the reaction medium (toluene or acetic acid) striking differences were observed in the development of enantiomeric excess with time-on-stream in continuous enantioselective hydrogenation of ethylbenzoylformate on cinchonidine-modified Pt/Al2O3, which correlated well with the amount of adsorbed cinchonidine on alumina and silica from acetic acid and toluene solutions. Maximally 93% enantiometric excess (ee) of (R)-ethyl mandelate was obtained.",

keywords = "Adsorption of cinchonidine, Bed dilution, Continuous hydrogenation",

author = "E. Toukoniitty and P. M{\"a}ki-Arvela and N. Kumar and T. Salmi and Murzin, {D. Yu}",

year = "2004",

month = jun,

doi = "10.1023/B:CATL.0000027292.23132.5c",

language = "English",

volume = "95",

pages = "179--183",

journal = "Catalysis Letters",

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TY - JOUR

T1 - Continuous enantioselective hydrogenation of ethylbenzoylformate over Pt/Al2O3 catalyst

T2 - Bed dilution effects and cinchonidine adsorption study

AU - Toukoniitty, E.

AU - Mäki-Arvela, P.

AU - Kumar, N.

AU - Salmi, T.

AU - Murzin, D. Yu

PY - 2004/6

Y1 - 2004/6

N2 - Depending on the reaction medium (toluene or acetic acid) striking differences were observed in the development of enantiomeric excess with time-on-stream in continuous enantioselective hydrogenation of ethylbenzoylformate on cinchonidine-modified Pt/Al2O3, which correlated well with the amount of adsorbed cinchonidine on alumina and silica from acetic acid and toluene solutions. Maximally 93% enantiometric excess (ee) of (R)-ethyl mandelate was obtained.

AB - Depending on the reaction medium (toluene or acetic acid) striking differences were observed in the development of enantiomeric excess with time-on-stream in continuous enantioselective hydrogenation of ethylbenzoylformate on cinchonidine-modified Pt/Al2O3, which correlated well with the amount of adsorbed cinchonidine on alumina and silica from acetic acid and toluene solutions. Maximally 93% enantiometric excess (ee) of (R)-ethyl mandelate was obtained.

KW - Adsorption of cinchonidine

KW - Bed dilution

KW - Continuous hydrogenation

UR - http://www.scopus.com/inward/record.url?scp=3543073977&partnerID=8YFLogxK

U2 - 10.1023/B:CATL.0000027292.23132.5c

DO - 10.1023/B:CATL.0000027292.23132.5c

M3 - Article

AN - SCOPUS:3543073977

SN - 1011-372X

VL - 95

SP - 179

EP - 183

JO - Catalysis Letters

JF - Catalysis Letters

IS - 3-4