Comparative safety evaluation of silica-based particles

H Kettiger, Didem Sen Karaman, L Schiesser, Jessica Rosenholm, J Huwyler

Tutkimustuotos: LehtiartikkeliArtikkeliTieteellinenvertaisarvioitu

27 Sitaatiot (Scopus)

Abstrakti

Silica nanoparticles (SNPs) are increasingly used as drug delivery systems (DDS) and for biomedical imaging. Therapeutic and diagnostic agents can be incorporated into the silica matrix to improve the stability and dissolution of drug substances in biological systems. However, the safety of SNPs as drug carriers remains controversial. To date, no validated and accepted nano-specific tests exist to predict the potentially harmful impact of these materials on the human body.
AlkuperäiskieliEi tiedossa
Sivut355–363
JulkaisuToxicology in Vitro
Vuosikerta30
Numero1
DOI - pysyväislinkit
TilaJulkaistu - 2015
OKM-julkaisutyyppiA1 Julkaistu artikkeli, soviteltu

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