Cellular stress response cross talk maintains protein and energy homeostasis

Cynthia L Swan; Lea Sistonen

doi:10.15252/embj.201490757

Cellular stress response cross talk maintains protein and energy homeostasis

Cynthia L Swan
, Lea Sistonen

Biokemia ja solubiologia

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

31 Sitaatiot (Scopus)

Abstrakti

Maintenance of cellular homeostasis depends upon several pathways that allow a cell to respond and adapt to both environmental stress and changes in metabolic status. New work in this issue of The EMBO Journal reveals a mechanism of cross talk between heat shock factor 1 (HSF1), the primary regulator of the proteotoxic stress response, and AMP-activated protein kinase (AMPK), the primary sensor in the metabolic stress response.

Alkuperäiskieli	Englanti
Sivut	267–269
Sivumäärä	3
Julkaisu	EMBO Journal
Vuosikerta	34
Numero	3
DOI - pysyväislinkit	https://doi.org/10.15252/embj.201490757
Tila	Julkaistu - 3 helmik. 2015
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

Pääsy asiakirjaan

10.15252/embj.201490757

Viittausmuodot

@article{4a3c5c3db17b44a39c128cf8a0b92ea2,

title = "Cellular stress response cross talk maintains protein and energy homeostasis",

abstract = "Maintenance of cellular homeostasis depends upon several pathways that allow a cell to respond and adapt to both environmental stress and changes in metabolic status. New work in this issue of The EMBO Journal reveals a mechanism of cross talk between heat shock factor 1 (HSF1), the primary regulator of the proteotoxic stress response, and AMP-activated protein kinase (AMPK), the primary sensor in the metabolic stress response.",

keywords = "AMP-Activated Protein Kinases/metabolism, Animals, DNA-Binding Proteins/metabolism, Heat Shock Transcription Factors, Neoplasm Proteins/metabolism, Neoplasms, Experimental/metabolism, Stress, Physiological, Transcription Factors/metabolism",

author = "Swan, \{Cynthia L\} and Lea Sistonen",

year = "2015",

month = feb,

day = "3",

doi = "10.15252/embj.201490757",

language = "English",

volume = "34",

pages = "267{\textendash}269",

journal = "EMBO Journal",

issn = "0261-4189",

publisher = "EMBO Press",

number = "3",

}

TY - JOUR

T1 - Cellular stress response cross talk maintains protein and energy homeostasis

AU - Swan, Cynthia L

AU - Sistonen, Lea

PY - 2015/2/3

Y1 - 2015/2/3

N2 - Maintenance of cellular homeostasis depends upon several pathways that allow a cell to respond and adapt to both environmental stress and changes in metabolic status. New work in this issue of The EMBO Journal reveals a mechanism of cross talk between heat shock factor 1 (HSF1), the primary regulator of the proteotoxic stress response, and AMP-activated protein kinase (AMPK), the primary sensor in the metabolic stress response.

AB - Maintenance of cellular homeostasis depends upon several pathways that allow a cell to respond and adapt to both environmental stress and changes in metabolic status. New work in this issue of The EMBO Journal reveals a mechanism of cross talk between heat shock factor 1 (HSF1), the primary regulator of the proteotoxic stress response, and AMP-activated protein kinase (AMPK), the primary sensor in the metabolic stress response.

KW - AMP-Activated Protein Kinases/metabolism

KW - Animals

KW - DNA-Binding Proteins/metabolism

KW - Heat Shock Transcription Factors

KW - Neoplasm Proteins/metabolism

KW - Neoplasms, Experimental/metabolism

KW - Stress, Physiological

KW - Transcription Factors/metabolism

U2 - 10.15252/embj.201490757

DO - 10.15252/embj.201490757

M3 - Article

C2 - 25555794

SN - 0261-4189

VL - 34

SP - 267

EP - 269

JO - EMBO Journal

JF - EMBO Journal

IS - 3

ER -

Cellular stress response cross talk maintains protein and energy homeostasis

Abstrakti

Pääsy asiakirjaan

Sormenjälki

Viittausmuodot