An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth

Pelin Kaya; Elisabeth Schaffner-Reckinger; Ganesh babu Manoharan; Vladimir Vukic; Alexandros Kiriazis; Mirko Ledda; Maria Burgos Renedo; Karolina Pavic; Anthoula Gaigneaux; Enrico Glaab; Daniel Kwaku Abankwa

doi:10.1021/acs.jmedchem.3c02129

An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth

Pelin Kaya
, Elisabeth Schaffner-Reckinger
, Ganesh babu Manoharan
, Vladimir Vukic
, Alexandros Kiriazis
, Mirko Ledda
, Maria Burgos Renedo
, Karolina Pavic
, Anthoula Gaigneaux
, Enrico Glaab
, Daniel Kwaku Abankwa

Turun biotiedekeskus

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

17 Sitaatiot (Scopus)

73 Lataukset (Pure)

Alkuperäiskieli	Englanti
Sivut	8569-8584
Sivumäärä	16
Julkaisu	Journal of Medicinal Chemistry
Vuosikerta	67
Numero	11
DOI - pysyväislinkit	https://doi.org/10.1021/acs.jmedchem.3c02129
Tila	Julkaistu - 17 toukok. 2024
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

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10.1021/acs.jmedchem.3c02129Lisenssi: CC BY

kaya-et-al-2024-an-improved-pde6d-inhibitor-combines-with-sildenafil-to-inhibit-kras-mutant-cancer-cell-growthLopullinen julkaistu versio, 5,5 MBLisenssi: CC BY

https://urn.fi/URN:NBN:fi-fe2025020710463

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@article{9c06b4a3248b43feada2246443be1f93,

title = "An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth",

keywords = "Assays, Toxicological synergy, Inhibitors, Cells, Bioluminescence",

author = "Pelin Kaya and Elisabeth Schaffner-Reckinger and Manoharan, \{Ganesh babu\} and Vladimir Vukic and Alexandros Kiriazis and Mirko Ledda and \{Burgos Renedo\}, Maria and Karolina Pavic and Anthoula Gaigneaux and Enrico Glaab and Abankwa, \{Daniel Kwaku\}",

year = "2024",

month = may,

day = "17",

doi = "10.1021/acs.jmedchem.3c02129",

language = "English",

volume = "67",

pages = "8569--8584",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American chemical society",

number = "11",

}

Kaya, P, Schaffner-Reckinger, E, Manoharan, GB, Vukic, V, Kiriazis, A, Ledda, M, Burgos Renedo, M, Pavic, K, Gaigneaux, A, Glaab, E & Abankwa, DK 2024, 'An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth', Journal of Medicinal Chemistry, Vuosikerta 67, Nro 11, Sivut 8569-8584. https://doi.org/10.1021/acs.jmedchem.3c02129

TY - JOUR

T1 - An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth

AU - Kaya, Pelin

AU - Schaffner-Reckinger, Elisabeth

AU - Manoharan, Ganesh babu

AU - Vukic, Vladimir

AU - Kiriazis, Alexandros

AU - Ledda, Mirko

AU - Burgos Renedo, Maria

AU - Pavic, Karolina

AU - Gaigneaux, Anthoula

AU - Glaab, Enrico

AU - Abankwa, Daniel Kwaku

PY - 2024/5/17

Y1 - 2024/5/17

KW - Assays

KW - Toxicological synergy

KW - Inhibitors

KW - Cells

KW - Bioluminescence

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=aboakademi&SrcAuth=WosAPI&KeyUT=WOS:001227329700001&DestLinkType=FullRecord&DestApp=WOS_CPL

U2 - 10.1021/acs.jmedchem.3c02129

DO - 10.1021/acs.jmedchem.3c02129

M3 - Article

C2 - 38758695

SN - 0022-2623

VL - 67

SP - 8569

EP - 8584

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 11

ER -

An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit <i>KRAS</i> Mutant Cancer Cell Growth

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