A Comprehensive Review of Patented Technologies to Fabricate Orodispersible Films: Proof of Patent Analysis (2000–2020)

Maram Suresh Gupta; Devegowda Vishakante Gowda; Tegginamath Pramod Kumar; Jessica M. Rosenholm

doi:10.3390/pharmaceutics14040820

A Comprehensive Review of Patented Technologies to Fabricate Orodispersible Films: Proof of Patent Analysis (2000–2020)

Maram Suresh Gupta, Devegowda Vishakante Gowda, Tegginamath Pramod Kumar, Jessica M. Rosenholm

Tutkimustuotos: Lehtiartikkeli › Artikkeli › Tieteellinen › vertaisarvioitu

13 Sitaatiot (Scopus)

118 Lataukset (Pure)

Abstrakti

Orodispersible films (ODFs)are ultra-thin, stamp-sized, rapidly disintegrating, and attractive oral drug delivery dosage forms best suited for the pediatric and geriatric patient populations.They can be fabricated by different techniques, but the most popular, simple, and industrially applicable technique is the solvent casting method (SCM). In addition, they can also be fabricated by extrusion, printing, electrospinning, and by a combination of these technologies (e.g., SCM + printing). The present review is aimed to provide a comprehensive overview of patented technologies of the last two decades to fabricate ODFs. Through this review, we present evidence to adamantly confirm that SCM is the most popular method while electrospinning is the most recent and upcoming method to fabricate ODFs. We also speculate around the more patent-protected technologies especially in the domain of printing (two or three-dimensional), extrusion (ram or hot-melt extrusion), and electrospinning, or a combination of the methods thereof.

Alkuperäiskieli	Englanti
Artikkeli	820
Sivumäärä	31
Julkaisu	Pharmaceutics
Vuosikerta	14
Numero	4
DOI - pysyväislinkit	https://doi.org/10.3390/pharmaceutics14040820
Tila	Julkaistu - 8 huhtik. 2022
OKM-julkaisutyyppi	A1 Julkaistu artikkeli, soviteltu

YK:n kestävän kehityksen tavoitteet

Tämä tuotos edistää seuraavia kestävän kehityksen tavoitteita:

Pääsy asiakirjaan

10.3390/pharmaceutics14040820Lisenssi: CC BY

pharmaceutics-14-00820-v2Lopullinen julkaistu versio, 12,9 MBLisenssi: CC BY

Muut tiedostot ja linkit

https://research.abo.fi/en/publications/dbf8cd93-a795-4d1c-945f-d56a4bce853a

Åbo Akademi Functional Printing Center
Toivakka, M. (PI), Rosenholm, J. (PI), Anttu, N. (PI), Bobacka, J. (PI), Huynh, T. P. (PI), Peltonen, J. (PI), Wang, X. (PI), Wilen, C.-E. (PI), Xu, C. (PI), Zhang, H. (PI) & Österbacka, R. (PI)
Faculty of Science and Engineering
Laitteistot/tilat: Laitos

AMBioPharma: Centre for Additive Manufacturing for Life Science and Pharmaceutical Industry
Rosenholm, J. (Vastuullinen tutkija), Xu, C. (Vastuullinen tutkija), Wang, X. (CoI) & Palo, M. (CoI)
01/09/21 → 31/08/23
Projekti: EU

Viittausmuodot

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title = "A Comprehensive Review of Patented Technologies to Fabricate Orodispersible Films: Proof of Patent Analysis (2000–2020)",

abstract = "Orodispersible films (ODFs)are ultra-thin, stamp-sized, rapidly disintegrating, and attractive oral drug delivery dosage forms best suited for the pediatric and geriatric patient populations.They can be fabricated by different techniques, but the most popular, simple, and industrially applicable technique is the solvent casting method (SCM). In addition, they can also be fabricated by extrusion, printing, electrospinning, and by a combination of these technologies (e.g., SCM + printing). The present review is aimed to provide a comprehensive overview of patented technologies of the last two decades to fabricate ODFs. Through this review, we present evidence to adamantly confirm that SCM is the most popular method while electrospinning is the most recent and upcoming method to fabricate ODFs. We also speculate around the more patent-protected technologies especially in the domain of printing (two or three-dimensional), extrusion (ram or hot-melt extrusion), and electrospinning, or a combination of the methods thereof.",

keywords = "Orodispersible films, Solvent casting, Printing technologies, Electrospinning",

author = "Gupta, {Maram Suresh} and Gowda, {Devegowda Vishakante} and Kumar, {Tegginamath Pramod} and Rosenholm, {Jessica M.}",

year = "2022",

month = apr,

day = "8",

doi = "10.3390/pharmaceutics14040820",

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AU - Gupta, Maram Suresh

AU - Gowda, Devegowda Vishakante

AU - Kumar, Tegginamath Pramod

AU - Rosenholm, Jessica M.

PY - 2022/4/8

Y1 - 2022/4/8

N2 - Orodispersible films (ODFs)are ultra-thin, stamp-sized, rapidly disintegrating, and attractive oral drug delivery dosage forms best suited for the pediatric and geriatric patient populations.They can be fabricated by different techniques, but the most popular, simple, and industrially applicable technique is the solvent casting method (SCM). In addition, they can also be fabricated by extrusion, printing, electrospinning, and by a combination of these technologies (e.g., SCM + printing). The present review is aimed to provide a comprehensive overview of patented technologies of the last two decades to fabricate ODFs. Through this review, we present evidence to adamantly confirm that SCM is the most popular method while electrospinning is the most recent and upcoming method to fabricate ODFs. We also speculate around the more patent-protected technologies especially in the domain of printing (two or three-dimensional), extrusion (ram or hot-melt extrusion), and electrospinning, or a combination of the methods thereof.

AB - Orodispersible films (ODFs)are ultra-thin, stamp-sized, rapidly disintegrating, and attractive oral drug delivery dosage forms best suited for the pediatric and geriatric patient populations.They can be fabricated by different techniques, but the most popular, simple, and industrially applicable technique is the solvent casting method (SCM). In addition, they can also be fabricated by extrusion, printing, electrospinning, and by a combination of these technologies (e.g., SCM + printing). The present review is aimed to provide a comprehensive overview of patented technologies of the last two decades to fabricate ODFs. Through this review, we present evidence to adamantly confirm that SCM is the most popular method while electrospinning is the most recent and upcoming method to fabricate ODFs. We also speculate around the more patent-protected technologies especially in the domain of printing (two or three-dimensional), extrusion (ram or hot-melt extrusion), and electrospinning, or a combination of the methods thereof.

KW - Orodispersible films

KW - Solvent casting

KW - Printing technologies

KW - Electrospinning

UR - https://research.abo.fi/en/publications/dbf8cd93-a795-4d1c-945f-d56a4bce853a

U2 - 10.3390/pharmaceutics14040820

DO - 10.3390/pharmaceutics14040820

M3 - Article

SN - 1999-4923

VL - 14

JO - Pharmaceutics

JF - Pharmaceutics

IS - 4

M1 - 820

ER -

A Comprehensive Review of Patented Technologies to Fabricate Orodispersible Films: Proof of Patent Analysis (2000–2020)

Abstrakti

YK:n kestävän kehityksen tavoitteet

Pääsy asiakirjaan

Muut tiedostot ja linkit

Sormenjälki

Laitteet

Åbo Akademi Functional Printing Center

Projektit

AMBioPharma: Centre for Additive Manufacturing for Life Science and Pharmaceutical Industry

Viittausmuodot