Mining Protein Aberrancies in Parkinson’s Disease from OMICs Data

Projektin tiedot

Description

Disturbed proteostasis may contribute to Parkinson’s disesase where deficient clearance of misfolded alpha-synuclein contributes to the pathology. Cells under stress are affected by this by a variety of mechanisms. From translational infidelity to usage of alternative start sites, the resulting protein aberrancies remain undetected by standard proteomics methods. This project will apply new methods to re-analyse existing proteomic data from Parkinson’s patient cohorts to uncover hidden proteome aberrancies within.
LyhytotsikkoMJFF Datascience
TilaPäättynyt
Todellinen alku/loppupvm01/06/2231/01/24

Rahoitus

  • Michael J. Fox Foundation