TY - JOUR
T1 - Ultrasensitive and Highly Selective o-Phenylenediamine Molecularly Imprinted Polymer for the Detection of 2,4-Dichlorophenoxyacetic Acid
AU - Tricase, Angelo
AU - Marchianò, Verdiana
AU - Macchia, Eleonora
AU - Ditaranto, Nicoletta
AU - Torsi, Luisa
AU - Bollella, Paolo
N1 - Publisher Copyright:
© 2024 The Author(s)
PY - 2024/8/1
Y1 - 2024/8/1
N2 - Herein, we report an ultrasensitive and highly selective analytical methods to detect 2,4-dichlorophenoxyacetic acid (2,4-D) using an o-phenylenediamine based molecularly imprinted polymer (o-PD-MIP) sensor. Electrochemical Quartz Crystal Microbalance (EQCM) is used to investigate both the kinetics and the mass of the electropolymerized o-phenylenediamine. Additionally, successful removal of the template from the imprinted cavities is confirmed by comparing the XP spectra of imprinted and o-PD-MIPs after various template removal procedures. The most effective method involves a 70:30 mixture of MeOH:H2O for 15 min under stirring. The o-PD-MIP sensor exhibits high sensitivity with a LoD of (3 ± 1) × 10−12 M, which is below the EU regulation limits for drinking water by six orders of magnitude, a linear range between 10 and 100pM, and an excellent selectivity. These results proved the effectiveness of template removal procedure by using a 70:30 MeOH:H2O mixture and are a proof-of-concept for ultrasensitive and selective 2,4-D detection in real samples.
AB - Herein, we report an ultrasensitive and highly selective analytical methods to detect 2,4-dichlorophenoxyacetic acid (2,4-D) using an o-phenylenediamine based molecularly imprinted polymer (o-PD-MIP) sensor. Electrochemical Quartz Crystal Microbalance (EQCM) is used to investigate both the kinetics and the mass of the electropolymerized o-phenylenediamine. Additionally, successful removal of the template from the imprinted cavities is confirmed by comparing the XP spectra of imprinted and o-PD-MIPs after various template removal procedures. The most effective method involves a 70:30 mixture of MeOH:H2O for 15 min under stirring. The o-PD-MIP sensor exhibits high sensitivity with a LoD of (3 ± 1) × 10−12 M, which is below the EU regulation limits for drinking water by six orders of magnitude, a linear range between 10 and 100pM, and an excellent selectivity. These results proved the effectiveness of template removal procedure by using a 70:30 MeOH:H2O mixture and are a proof-of-concept for ultrasensitive and selective 2,4-D detection in real samples.
KW - 2,4-dichlorofenoxyacetic acid
KW - Modified electrodes
KW - Molecularly imprinted polymers (MIPs)
KW - o-phenylenediamine
KW - Template removal
UR - http://www.scopus.com/inward/record.url?scp=85193439365&partnerID=8YFLogxK
U2 - 10.1016/j.electacta.2024.144430
DO - 10.1016/j.electacta.2024.144430
M3 - Article
AN - SCOPUS:85193439365
SN - 0013-4686
VL - 494
JO - Electrochimica Acta
JF - Electrochimica Acta
M1 - 144430
ER -