Titania nanofibers in gypsum composites: an antibacterial and cytotoxicology study

Melinda Mohl; Aron Dombovari; Elena S. Tuchina; Pavel O. Petrov; Olga A. Bibikova; Ilya Skovorodkin; Alexey P. Popov; Anne-Riikka Rautio; Anjana Sarkar; Jyri-Pekka Mikkola; Mika Huuhtanen; Seppo Vainio; Riitta L. Keiski; Arthur Prilepsky; Akos Kukovecz; Zoltan Konya; Valery V. Tuchin; Krisztian Kordas

doi:10.1039/c3tb21644f

Titania nanofibers in gypsum composites: an antibacterial and cytotoxicology study

Melinda Mohl, Aron Dombovari, Elena S. Tuchina, Pavel O. Petrov, Olga A. Bibikova, Ilya Skovorodkin, Alexey P. Popov, Anne-Riikka Rautio, Anjana Sarkar, Jyri-Pekka Mikkola, Mika Huuhtanen, Seppo Vainio, Riitta L. Keiski, Arthur Prilepsky, Akos Kukovecz, Zoltan Konya, Valery V. Tuchin, Krisztian Kordas

Research output: Contribution to journal › Article › Scientific › peer-review

18 Citations (Scopus)

Abstract

Further developments of antibacterial coatings based on photocatalytic nanomaterials could be a promising route towards potential environmentally friendly applications in households, public buildings and health care facilities. Hereby we describe a simple chemical approach to synthesize photocatalytic nanomaterial-embedded coatings using gypsum as a binder. Various types of TiO2 nanofiber-based photocatalytic materials (nitrogen-doped and/or palladium nanoparticle decorated) and their composites with gypsum were characterized by means of scanning (SEM) and transmission (TEM) electron microscopy as well as electron and X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDX) techniques. These gypsum-based composites can be directly applied as commercially available paints on indoor walls. Herein we report that surfaces coated with photocatalytic composites exhibit excellent antimicrobial properties by killing both methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) under blue light. In the case of MSSA cells, the palladium nanoparticle-decorated and nitrogen-doped TiO2 composites demonstrated the highest antimicrobial activity. For the MRSA strain even pure gypsum samples were proven to be efficient in eradicating Gram-positive human pathogens. The cytotoxicity of freestanding TiO2 nanofibers was revealed by analyzing the viability of HeLa cells using MTT and fluorescent cell assays.

Original language	Undefined/Unknown
Pages (from-to)	1307–1316
Journal	Journal of Materials Chemistry. B
Volume	2
Issue number	10
DOIs	https://doi.org/10.1039/c3tb21644f
Publication status	Published - 2014
MoE publication type	A1 Journal article-refereed

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10.1039/c3tb21644f

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Mohl, M., Dombovari, A., Tuchina, E. S., Petrov, P. O., Bibikova, O. A., Skovorodkin, I., Popov, A. P., Rautio, A.-R., Sarkar, A., Mikkola, J.-P., Huuhtanen, M., Vainio, S., Keiski, R. L., Prilepsky, A., Kukovecz, A., Konya, Z., Tuchin, V. V., & Kordas, K. (2014). Titania nanofibers in gypsum composites: an antibacterial and cytotoxicology study. Journal of Materials Chemistry. B, 2(10), 1307–1316. https://doi.org/10.1039/c3tb21644f

@article{52e671b85a264477ac1f30c1f7894fd8,

title = "Titania nanofibers in gypsum composites: an antibacterial and cytotoxicology study",

abstract = "Further developments of antibacterial coatings based on photocatalytic nanomaterials could be a promising route towards potential environmentally friendly applications in households, public buildings and health care facilities. Hereby we describe a simple chemical approach to synthesize photocatalytic nanomaterial-embedded coatings using gypsum as a binder. Various types of TiO2 nanofiber-based photocatalytic materials (nitrogen-doped and/or palladium nanoparticle decorated) and their composites with gypsum were characterized by means of scanning (SEM) and transmission (TEM) electron microscopy as well as electron and X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDX) techniques. These gypsum-based composites can be directly applied as commercially available paints on indoor walls. Herein we report that surfaces coated with photocatalytic composites exhibit excellent antimicrobial properties by killing both methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) under blue light. In the case of MSSA cells, the palladium nanoparticle-decorated and nitrogen-doped TiO2 composites demonstrated the highest antimicrobial activity. For the MRSA strain even pure gypsum samples were proven to be efficient in eradicating Gram-positive human pathogens. The cytotoxicity of freestanding TiO2 nanofibers was revealed by analyzing the viability of HeLa cells using MTT and fluorescent cell assays.",

author = "Melinda Mohl and Aron Dombovari and Tuchina, {Elena S.} and Petrov, {Pavel O.} and Bibikova, {Olga A.} and Ilya Skovorodkin and Popov, {Alexey P.} and Anne-Riikka Rautio and Anjana Sarkar and Jyri-Pekka Mikkola and Mika Huuhtanen and Seppo Vainio and Keiski, {Riitta L.} and Arthur Prilepsky and Akos Kukovecz and Zoltan Konya and Tuchin, {Valery V.} and Krisztian Kordas",

year = "2014",

doi = "10.1039/c3tb21644f",

language = "Odefinierat/ok{\"a}nt",

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pages = "1307–1316",

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Mohl, M, Dombovari, A, Tuchina, ES, Petrov, PO, Bibikova, OA, Skovorodkin, I, Popov, AP, Rautio, A-R, Sarkar, A, Mikkola, J-P, Huuhtanen, M, Vainio, S, Keiski, RL, Prilepsky, A, Kukovecz, A, Konya, Z, Tuchin, VV & Kordas, K 2014, 'Titania nanofibers in gypsum composites: an antibacterial and cytotoxicology study', Journal of Materials Chemistry. B, vol. 2, no. 10, pp. 1307–1316. https://doi.org/10.1039/c3tb21644f

TY - JOUR

T1 - Titania nanofibers in gypsum composites: an antibacterial and cytotoxicology study

AU - Mohl, Melinda

AU - Dombovari, Aron

AU - Tuchina, Elena S.

AU - Petrov, Pavel O.

AU - Bibikova, Olga A.

AU - Skovorodkin, Ilya

AU - Popov, Alexey P.

AU - Rautio, Anne-Riikka

AU - Sarkar, Anjana

AU - Mikkola, Jyri-Pekka

AU - Huuhtanen, Mika

AU - Vainio, Seppo

AU - Keiski, Riitta L.

AU - Prilepsky, Arthur

AU - Kukovecz, Akos

AU - Konya, Zoltan

AU - Tuchin, Valery V.

AU - Kordas, Krisztian

PY - 2014

Y1 - 2014

N2 - Further developments of antibacterial coatings based on photocatalytic nanomaterials could be a promising route towards potential environmentally friendly applications in households, public buildings and health care facilities. Hereby we describe a simple chemical approach to synthesize photocatalytic nanomaterial-embedded coatings using gypsum as a binder. Various types of TiO2 nanofiber-based photocatalytic materials (nitrogen-doped and/or palladium nanoparticle decorated) and their composites with gypsum were characterized by means of scanning (SEM) and transmission (TEM) electron microscopy as well as electron and X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDX) techniques. These gypsum-based composites can be directly applied as commercially available paints on indoor walls. Herein we report that surfaces coated with photocatalytic composites exhibit excellent antimicrobial properties by killing both methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) under blue light. In the case of MSSA cells, the palladium nanoparticle-decorated and nitrogen-doped TiO2 composites demonstrated the highest antimicrobial activity. For the MRSA strain even pure gypsum samples were proven to be efficient in eradicating Gram-positive human pathogens. The cytotoxicity of freestanding TiO2 nanofibers was revealed by analyzing the viability of HeLa cells using MTT and fluorescent cell assays.

AB - Further developments of antibacterial coatings based on photocatalytic nanomaterials could be a promising route towards potential environmentally friendly applications in households, public buildings and health care facilities. Hereby we describe a simple chemical approach to synthesize photocatalytic nanomaterial-embedded coatings using gypsum as a binder. Various types of TiO2 nanofiber-based photocatalytic materials (nitrogen-doped and/or palladium nanoparticle decorated) and their composites with gypsum were characterized by means of scanning (SEM) and transmission (TEM) electron microscopy as well as electron and X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDX) techniques. These gypsum-based composites can be directly applied as commercially available paints on indoor walls. Herein we report that surfaces coated with photocatalytic composites exhibit excellent antimicrobial properties by killing both methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) under blue light. In the case of MSSA cells, the palladium nanoparticle-decorated and nitrogen-doped TiO2 composites demonstrated the highest antimicrobial activity. For the MRSA strain even pure gypsum samples were proven to be efficient in eradicating Gram-positive human pathogens. The cytotoxicity of freestanding TiO2 nanofibers was revealed by analyzing the viability of HeLa cells using MTT and fluorescent cell assays.

U2 - 10.1039/c3tb21644f

DO - 10.1039/c3tb21644f

M3 - Artikel

SN - 2050-750X

VL - 2

SP - 1307

EP - 1316

JO - Journal of Materials Chemistry. B

JF - Journal of Materials Chemistry. B

IS - 10

ER -