Titania nanofibers in gypsum composites: an antibacterial and cytotoxicology study

Melinda Mohl, Aron Dombovari, Elena S. Tuchina, Pavel O. Petrov, Olga A. Bibikova, Ilya Skovorodkin, Alexey P. Popov, Anne-Riikka Rautio, Anjana Sarkar, Jyri-Pekka Mikkola, Mika Huuhtanen, Seppo Vainio, Riitta L. Keiski, Arthur Prilepsky, Akos Kukovecz, Zoltan Konya, Valery V. Tuchin, Krisztian Kordas

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    18 Citations (Scopus)


    Further developments of antibacterial coatings based on photocatalytic nanomaterials could be a promising route towards potential environmentally friendly applications in households, public buildings and health care facilities. Hereby we describe a simple chemical approach to synthesize photocatalytic nanomaterial-embedded coatings using gypsum as a binder. Various types of TiO2 nanofiber-based photocatalytic materials (nitrogen-doped and/or palladium nanoparticle decorated) and their composites with gypsum were characterized by means of scanning (SEM) and transmission (TEM) electron microscopy as well as electron and X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDX) techniques. These gypsum-based composites can be directly applied as commercially available paints on indoor walls. Herein we report that surfaces coated with photocatalytic composites exhibit excellent antimicrobial properties by killing both methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) under blue light. In the case of MSSA cells, the palladium nanoparticle-decorated and nitrogen-doped TiO2 composites demonstrated the highest antimicrobial activity. For the MRSA strain even pure gypsum samples were proven to be efficient in eradicating Gram-positive human pathogens. The cytotoxicity of freestanding TiO2 nanofibers was revealed by analyzing the viability of HeLa cells using MTT and fluorescent cell assays.
    Original languageUndefined/Unknown
    Pages (from-to)1307–1316
    JournalJournal of Materials Chemistry. B
    Issue number10
    Publication statusPublished - 2014
    MoE publication typeA1 Journal article-refereed

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