Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins

E Mantzouki; M Lurling; J Fastner; LD Domis; E Wilk-Wozniak; J Koreiviene; L Seelen; S Teurlincx; Y Verstijnen; W Krzton; E Walusiak; J Karosiene; J Kasperoviciene; K Savadova; I Vitonyte; C Cillero-Castro; A Budzynska; R Goldyn; A Kozak; J Rosinska; E Szelag-Wasielewska; P Domek; N Jakubowska-Krepska; K Kwasizur; B Messyasz; A Pelechata; M Pelechaty; M Kokocinski; A Garcia-Murcia; M Real; E Romans; J Noguero-Ribes; DP Duque; E Fernandez-Moran; N Karakaya; Kerstin Häggqvist; N Demir; M Beklioglu; N Filiz; EE Levi; U Iskin; G Bezirci; UN Tavsanoglu; K Ozhan; S Gkelis; M Panou; O Fakioglu; C Avagianos; T Kaloudis; K Celik; M Yilmaz; R Marce; N Catalan; AG Bravo; M Buck; W Colom-Montero; K Mustonen; D Pierson; Y Yang; PM Raposeiro; V Goncalves; MG Antoniou; N Tsiarta; V McCarthy; VC Perello

doi:10.3390/toxins10040156

Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins

E Mantzouki, M Lurling, J Fastner, LD Domis, E Wilk-Wozniak, J Koreiviene, L Seelen, S Teurlincx, Y Verstijnen, W Krzton, E Walusiak, J Karosiene, J Kasperoviciene, K Savadova, I Vitonyte, C Cillero-Castro, A Budzynska, R Goldyn, A Kozak, J RosinskaE Szelag-Wasielewska, P Domek, N Jakubowska-Krepska, K Kwasizur, B Messyasz, A Pelechata, M Pelechaty, M Kokocinski, A Garcia-Murcia, M Real, E Romans, J Noguero-Ribes, DP Duque, E Fernandez-Moran, N Karakaya, Kerstin Häggqvist, N Demir, M Beklioglu, N Filiz, EE Levi, U Iskin, G Bezirci, UN Tavsanoglu, K Ozhan, S Gkelis, M Panou, O Fakioglu, C Avagianos, T Kaloudis, K Celik, M Yilmaz, R Marce, N Catalan, AG Bravo, M Buck, W Colom-Montero, K Mustonen, D Pierson, Y Yang, PM Raposeiro, V Goncalves, MG Antoniou, N Tsiarta, V McCarthy, VC Perello

Research output: Contribution to journal › Article › Scientific › peer-review

159 Citations (Scopus)

Abstract

Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other classes, such as neurotoxins (e.g., anatoxin-a) and cytotoxins (e.g., cylindrospermopsin) due to their potency. Most studies examine the relationship between individual toxin variants and environmental factors, such as nutrients, temperature and light. In summer 2015, we collected samples across Europe to investigate the effect of nutrient and temperature gradients on the variability of toxin production at a continental scale. Direct and indirect effects of temperature were the main drivers of the spatial distribution in the toxins produced by the cyanobacterial community, the toxin concentrations and toxin quota. Generalized linear models showed that a Toxin Diversity Index (TDI) increased with latitude, while it decreased with water stability. Increases in TDI were explained through a significant increase in toxin variants such as MC-YR, anatoxin and cylindrospermopsin, accompanied by a decreasing presence of MC-LR. While global warming continues, the direct and indirect effects of increased lake temperatures will drive changes in the distribution of cyanobacterial toxins in Europe, potentially promoting selection of a few highly toxic species or strains.

Original language	Undefined/Unknown
Pages (from-to)	–
Number of pages	24
Journal	Toxins
Volume	10
Issue number	4
DOIs	https://doi.org/10.3390/toxins10040156
Publication status	Published - 2018
MoE publication type	A1 Journal article-refereed

Keywords

anatoxin
direct effects
spatial distribution
European Multi Lake Survey
Indirect effects
Cylindrospermopsin

Access to Document

10.3390/toxins10040156

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923322/

Cite this

Mantzouki, E., Lurling, M., Fastner, J., Domis, LD., Wilk-Wozniak, E., Koreiviene, J., Seelen, L., Teurlincx, S., Verstijnen, Y., Krzton, W., Walusiak, E., Karosiene, J., Kasperoviciene, J., Savadova, K., Vitonyte, I., Cillero-Castro, C., Budzynska, A., Goldyn, R., Kozak, A., ... Perello, VC. (2018). Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins. Toxins, 10(4), –. https://doi.org/10.3390/toxins10040156

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title = "Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins",

abstract = "Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other classes, such as neurotoxins (e.g., anatoxin-a) and cytotoxins (e.g., cylindrospermopsin) due to their potency. Most studies examine the relationship between individual toxin variants and environmental factors, such as nutrients, temperature and light. In summer 2015, we collected samples across Europe to investigate the effect of nutrient and temperature gradients on the variability of toxin production at a continental scale. Direct and indirect effects of temperature were the main drivers of the spatial distribution in the toxins produced by the cyanobacterial community, the toxin concentrations and toxin quota. Generalized linear models showed that a Toxin Diversity Index (TDI) increased with latitude, while it decreased with water stability. Increases in TDI were explained through a significant increase in toxin variants such as MC-YR, anatoxin and cylindrospermopsin, accompanied by a decreasing presence of MC-LR. While global warming continues, the direct and indirect effects of increased lake temperatures will drive changes in the distribution of cyanobacterial toxins in Europe, potentially promoting selection of a few highly toxic species or strains.",

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author = "E Mantzouki and M Lurling and J Fastner and LD Domis and E Wilk-Wozniak and J Koreiviene and L Seelen and S Teurlincx and Y Verstijnen and W Krzton and E Walusiak and J Karosiene and J Kasperoviciene and K Savadova and I Vitonyte and C Cillero-Castro and A Budzynska and R Goldyn and A Kozak and J Rosinska and E Szelag-Wasielewska and P Domek and N Jakubowska-Krepska and K Kwasizur and B Messyasz and A Pelechata and M Pelechaty and M Kokocinski and A Garcia-Murcia and M Real and E Romans and J Noguero-Ribes and DP Duque and E Fernandez-Moran and N Karakaya and Kerstin H{\"a}ggqvist and N Demir and M Beklioglu and N Filiz and EE Levi and U Iskin and G Bezirci and UN Tavsanoglu and K Ozhan and S Gkelis and M Panou and O Fakioglu and C Avagianos and T Kaloudis and K Celik and M Yilmaz and R Marce and N Catalan and AG Bravo and M Buck and W Colom-Montero and K Mustonen and D Pierson and Y Yang and PM Raposeiro and V Goncalves and MG Antoniou and N Tsiarta and V McCarthy and VC Perello",

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Mantzouki, E, Lurling, M, Fastner, J, Domis, LD, Wilk-Wozniak, E, Koreiviene, J, Seelen, L, Teurlincx, S, Verstijnen, Y, Krzton, W, Walusiak, E, Karosiene, J, Kasperoviciene, J, Savadova, K, Vitonyte, I, Cillero-Castro, C, Budzynska, A, Goldyn, R, Kozak, A, Rosinska, J, Szelag-Wasielewska, E, Domek, P, Jakubowska-Krepska, N, Kwasizur, K, Messyasz, B, Pelechata, A, Pelechaty, M, Kokocinski, M, Garcia-Murcia, A, Real, M, Romans, E, Noguero-Ribes, J, Duque, DP, Fernandez-Moran, E, Karakaya, N, Häggqvist, K, Demir, N, Beklioglu, M, Filiz, N, Levi, EE, Iskin, U, Bezirci, G, Tavsanoglu, UN, Ozhan, K, Gkelis, S, Panou, M, Fakioglu, O, Avagianos, C, Kaloudis, T, Celik, K, Yilmaz, M, Marce, R, Catalan, N, Bravo, AG, Buck, M, Colom-Montero, W, Mustonen, K, Pierson, D, Yang, Y, Raposeiro, PM, Goncalves, V, Antoniou, MG, Tsiarta, N, McCarthy, V & Perello, VC 2018, 'Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins', Toxins, vol. 10, no. 4, pp. –. https://doi.org/10.3390/toxins10040156

TY - JOUR

T1 - Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins

AU - Mantzouki, E

AU - Lurling, M

AU - Fastner, J

AU - Domis, LD

AU - Wilk-Wozniak, E

AU - Koreiviene, J

AU - Seelen, L

AU - Teurlincx, S

AU - Verstijnen, Y

AU - Krzton, W

AU - Walusiak, E

AU - Karosiene, J

AU - Kasperoviciene, J

AU - Savadova, K

AU - Vitonyte, I

AU - Cillero-Castro, C

AU - Budzynska, A

AU - Goldyn, R

AU - Kozak, A

AU - Rosinska, J

AU - Szelag-Wasielewska, E

AU - Domek, P

AU - Jakubowska-Krepska, N

AU - Kwasizur, K

AU - Messyasz, B

AU - Pelechata, A

AU - Pelechaty, M

AU - Kokocinski, M

AU - Garcia-Murcia, A

AU - Real, M

AU - Romans, E

AU - Noguero-Ribes, J

AU - Duque, DP

AU - Fernandez-Moran, E

AU - Karakaya, N

AU - Häggqvist, Kerstin

AU - Demir, N

AU - Beklioglu, M

AU - Filiz, N

AU - Levi, EE

AU - Iskin, U

AU - Bezirci, G

AU - Tavsanoglu, UN

AU - Ozhan, K

AU - Gkelis, S

AU - Panou, M

AU - Fakioglu, O

AU - Avagianos, C

AU - Kaloudis, T

AU - Celik, K

AU - Yilmaz, M

AU - Marce, R

AU - Catalan, N

AU - Bravo, AG

AU - Buck, M

AU - Colom-Montero, W

AU - Mustonen, K

AU - Pierson, D

AU - Yang, Y

AU - Raposeiro, PM

AU - Goncalves, V

AU - Antoniou, MG

AU - Tsiarta, N

AU - McCarthy, V

AU - Perello, VC

PY - 2018

Y1 - 2018

N2 - Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other classes, such as neurotoxins (e.g., anatoxin-a) and cytotoxins (e.g., cylindrospermopsin) due to their potency. Most studies examine the relationship between individual toxin variants and environmental factors, such as nutrients, temperature and light. In summer 2015, we collected samples across Europe to investigate the effect of nutrient and temperature gradients on the variability of toxin production at a continental scale. Direct and indirect effects of temperature were the main drivers of the spatial distribution in the toxins produced by the cyanobacterial community, the toxin concentrations and toxin quota. Generalized linear models showed that a Toxin Diversity Index (TDI) increased with latitude, while it decreased with water stability. Increases in TDI were explained through a significant increase in toxin variants such as MC-YR, anatoxin and cylindrospermopsin, accompanied by a decreasing presence of MC-LR. While global warming continues, the direct and indirect effects of increased lake temperatures will drive changes in the distribution of cyanobacterial toxins in Europe, potentially promoting selection of a few highly toxic species or strains.

AB - Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other classes, such as neurotoxins (e.g., anatoxin-a) and cytotoxins (e.g., cylindrospermopsin) due to their potency. Most studies examine the relationship between individual toxin variants and environmental factors, such as nutrients, temperature and light. In summer 2015, we collected samples across Europe to investigate the effect of nutrient and temperature gradients on the variability of toxin production at a continental scale. Direct and indirect effects of temperature were the main drivers of the spatial distribution in the toxins produced by the cyanobacterial community, the toxin concentrations and toxin quota. Generalized linear models showed that a Toxin Diversity Index (TDI) increased with latitude, while it decreased with water stability. Increases in TDI were explained through a significant increase in toxin variants such as MC-YR, anatoxin and cylindrospermopsin, accompanied by a decreasing presence of MC-LR. While global warming continues, the direct and indirect effects of increased lake temperatures will drive changes in the distribution of cyanobacterial toxins in Europe, potentially promoting selection of a few highly toxic species or strains.

KW - anatoxin

KW - direct effects

KW - spatial distribution

KW - European Multi Lake Survey

KW - Indirect effects

KW - Cylindrospermopsin

KW - anatoxin

KW - direct effects

KW - spatial distribution

KW - European Multi Lake Survey

KW - Indirect effects

KW - Cylindrospermopsin

KW - anatoxin

KW - direct effects

KW - spatial distribution

KW - European Multi Lake Survey

KW - Indirect effects

KW - Cylindrospermopsin

U2 - 10.3390/toxins10040156

DO - 10.3390/toxins10040156

M3 - Artikel

SN - 2072-6651

VL - 10

SP - –

JO - Toxins

JF - Toxins

IS - 4

ER -