Synthesis of Spirocyclic Ethers

S Rosenberg, Reko Leino

    Research output: Contribution to journalReview Article or Literature Reviewpeer-review

    69 Citations (Scopus)


    Spirocycles, including spirocyclic ethers, occur frequently in natural products and pharmaceutically active substances. Accordingly, synthetic methodologies utilized for the preparation of such compounds are of broad interest. The present review focuses on the general synthetic approaches that have been utilized for the construction of spirocyclic ethers during the past two decades.
    Original languageUndefined/Unknown
    Pages (from-to)2651–2673
    Number of pages23
    Issue number16
    Publication statusPublished - 2009
    MoE publication typeA2 Review article in a scientific journal


    • ethers
    • natural products
    • ring closure
    • spiro compounds
    • stereoselective synthesis

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