Synthesis of pharmaceutically active compounds containing a disubstituted piperidine framework

S Kallstrom, Reko Leino

    Research output: Contribution to journalArticleScientificpeer-review

    175 Citations (Scopus)

    Abstract

    The synthesis of pharmaceutically active compounds bearing a disubstituted piperidine framework is reviewed. Due to their frequent Occurrence in pharmaceutical research, functionalized piperidines and the synthetic methodologies used for their preparation are of considerable topical interest. The present review focuses on the synthetic pathways used for the preparation of disubstituted piperidines and also briefly covers the activity and/or usage of the same. (c) 2007 Elsevier Ltd. All rights reserved.
    Original languageUndefined/Unknown
    Pages (from-to)601–635
    Number of pages35
    JournalBioorganic and Medicinal Chemistry
    Volume16
    Issue number2
    DOIs
    Publication statusPublished - 2008
    MoE publication typeA1 Journal article-refereed

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