Synthesis of pharmaceutically active compounds containing a disubstituted piperidine framework

S Kallstrom; Reko Leino

doi:10.1016/j.bmc.2007.10.018

Synthesis of pharmaceutically active compounds containing a disubstituted piperidine framework

S Kallstrom, Reko Leino

Research output: Contribution to journal › Review Article or Literature Review › peer-review

202 Citations (Scopus)

Abstract

The synthesis of pharmaceutically active compounds bearing a disubstituted piperidine framework is reviewed. Due to their frequent Occurrence in pharmaceutical research, functionalized piperidines and the synthetic methodologies used for their preparation are of considerable topical interest. The present review focuses on the synthetic pathways used for the preparation of disubstituted piperidines and also briefly covers the activity and/or usage of the same. (c) 2007 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	601–635
Number of pages	35
Journal	Bioorganic and Medicinal Chemistry
Volume	16
Issue number	2
DOIs	https://doi.org/10.1016/j.bmc.2007.10.018
Publication status	Published - 2008
MoE publication type	A2 Review article in a scientific journal

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title = "Synthesis of pharmaceutically active compounds containing a disubstituted piperidine framework",

abstract = "The synthesis of pharmaceutically active compounds bearing a disubstituted piperidine framework is reviewed. Due to their frequent Occurrence in pharmaceutical research, functionalized piperidines and the synthetic methodologies used for their preparation are of considerable topical interest. The present review focuses on the synthetic pathways used for the preparation of disubstituted piperidines and also briefly covers the activity and/or usage of the same. (c) 2007 Elsevier Ltd. All rights reserved.",

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AU - Kallstrom, S

AU - Leino, Reko

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AB - The synthesis of pharmaceutically active compounds bearing a disubstituted piperidine framework is reviewed. Due to their frequent Occurrence in pharmaceutical research, functionalized piperidines and the synthetic methodologies used for their preparation are of considerable topical interest. The present review focuses on the synthetic pathways used for the preparation of disubstituted piperidines and also briefly covers the activity and/or usage of the same. (c) 2007 Elsevier Ltd. All rights reserved.

U2 - 10.1016/j.bmc.2007.10.018

DO - 10.1016/j.bmc.2007.10.018

M3 - Review Article or Literature Review

SN - 0968-0896

VL - 16

SP - 601

EP - 635

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

IS - 2

ER -

Synthesis of pharmaceutically active compounds containing a disubstituted piperidine framework

Abstract

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