Abstract
Conclusions: The incorporated MAL linkage in [Cu-64]NODAGA-MAL-exendin-4 was unable to reduce kidney radioactivity levels, compared to [Cu-64]NODAGA-exendin-4. The applicability of metabolizable linkages in the design of kidney-saving exendin-4 analogs requires further investigation. (C) 2013 Elsevier Inc. All rights reserved.
Original language | Undefined/Unknown |
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Pages (from-to) | 1006–1012 |
Number of pages | 7 |
Journal | Nuclear Medicine and Biology |
Volume | 40 |
Issue number | 8 |
DOIs | |
Publication status | Published - 2013 |
MoE publication type | A1 Journal article-refereed |
Keywords
- Copper-64
- Exendin
- GLP-1 receptor
- NODAGA
- Renal brush border membrane