Structure of a hepatotoxic pentapeptide from the cyanobacterium Nodularia spumigena

Sandström, Glemarec, Jussi Meriluoto, John Eriksson, Chattopadhyaya

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    Abstract

    The structure of a hepatotoxic peptide from the cyanobacterium Nodularia spumigena was determined using 1D and 2D proton nuclear magnetic resonance spectroscopy and fast atom bombardment mass spectrometry. The toxin was a cyclic pentapeptide (mol. wt 824.5) with the structure cyclo-(beta-methylisoAsp-Arg-Adda-isoGlu-N-methylde hydrobutyric acid) (Adda: 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid).
    Original languageUndefined/Unknown
    Pages (from-to)535–540
    JournalToxicon
    Volume28
    Issue number5
    Publication statusPublished - 1990
    MoE publication typeA1 Journal article-refereed

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