Abstract
A method for the glycosylation of anthracyclines featuring benzoylated imidate donors has been developed and utilized in the synthesis of glycosylated 4-deoxy-epsilon-rhodomycinone derivatives. Due to its high efficiency, regioselectivity, stereoselectivity, and operational simplicity, the method should prove valuable to researchers working with glycosylation of tetracyclic compounds. (C) 2011 Elsevier Ltd. All rights reserved.
| Original language | Undefined/Unknown |
|---|---|
| Pages (from-to) | 858–862 |
| Number of pages | 5 |
| Journal | Carbohydrate Research |
| Volume | 346 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2011 |
| MoE publication type | A1 Journal article-refereed |
Keywords
- Anthracycline
- Glycosylation
- Regioselectivite synthesis
- Rhodomycinone glycosides
- Stereoselective synthesis