Solid Lipid Nanoparticles: Emerging Colloidal Nano Drug Delivery Systems

V Mishra, Kuldeep Bansal, A Verma, N Yadav, S Thakur, K Sudhakar, Jessica Rosenholm

Research output: Contribution to journalArticleScientificpeer-review

82 Citations (Scopus)
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Abstract

Solid lipid nanoparticles (SLNs) are nanocarriers developed as substitute colloidal drug delivery systems parallel to liposomes, lipid emulsions, polymeric nanoparticles, and so forth. Owing to their unique size dependent properties and ability to incorporate drugs, SLNs present an opportunity to build up new therapeutic prototypes for drug delivery and targeting. SLNs hold great potential for attaining the goal of targeted and controlled drug delivery, which currently draws the interest of researchers worldwide. The present review sheds light on different aspects of SLNs including fabrication and characterization techniques, formulation variables, routes of administration, surface modifications, toxicity, and biomedical applications.
Original languageUndefined/Unknown
Pages (from-to)
JournalPharmaceutics
Volume10
Issue number4
DOIs
Publication statusPublished - 2018
MoE publication typeA1 Journal article-refereed

Keywords

  • drug delivery
  • drug-delivery systems
  • Colloidal nanoparticles
  • cytotoxicity
  • solid lipid
  • Nanoparticles

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