Single therapeutic dose of an antiviral UL29 siRNA swarm diminishes symptoms and viral load of mice infected intranasally with HSV‐1

Tuomas Lasanen; Fanny Frejborg; Liisa M. Lund; Marie C. Nyman; Julius Orpana; Huda Habib; Salla Alaollitervo; Alesia A. Levanova; Minna M. Poranen; Veijo Hukkanen; Kiira Kalke

doi:10.1002/SMMD.20230009

Single therapeutic dose of an antiviral UL29 siRNA swarm diminishes symptoms and viral load of mice infected intranasally with HSV‐1

Tuomas Lasanen
, Fanny Frejborg^*
, Liisa M. Lund
, Marie C. Nyman
, Julius Orpana
, Huda Habib
, Salla Alaollitervo
, Alesia A. Levanova
, Minna M. Poranen
, Veijo Hukkanen
, Kiira Kalke

^*Corresponding author for this work

Doctoral Network in Informational and Structural Biology

Research output: Contribution to journal › Article › Scientific › peer-review

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Original language	English
Article number	e20230009
Number of pages	10
Journal	Smart Medicine
DOIs	https://doi.org/10.1002/SMMD.20230009
Publication status	Published - 10 May 2023
MoE publication type	A1 Journal article-refereed

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10.1002/SMMD.20230009Licence: CC BY

Smart Medicine - 2023 - LasanenFinal published version, 1.18 MBLicence: CC BY

https://urn.fi/URN:NBN:fi-fe20230925136271

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Lasanen, T., Frejborg, F., Lund, L. M., Nyman, M. C., Orpana, J., Habib, H., Alaollitervo, S., Levanova, A. A., Poranen, M. M., Hukkanen, V., & Kalke, K. (2023). Single therapeutic dose of an antiviral UL29 siRNA swarm diminishes symptoms and viral load of mice infected intranasally with HSV‐1. Smart Medicine, Article e20230009. https://doi.org/10.1002/SMMD.20230009

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title = "Single therapeutic dose of an antiviral UL29 siRNA swarm diminishes symptoms and viral load of mice infected intranasally with HSV‐1",

author = "Tuomas Lasanen and Fanny Frejborg and Lund, \{Liisa M.\} and Nyman, \{Marie C.\} and Julius Orpana and Huda Habib and Salla Alaollitervo and Levanova, \{Alesia A.\} and Poranen, \{Minna M.\} and Veijo Hukkanen and Kiira Kalke",

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doi = "10.1002/SMMD.20230009",

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T1 - Single therapeutic dose of an antiviral UL29 siRNA swarm diminishes symptoms and viral load of mice infected intranasally with HSV‐1

AU - Lasanen, Tuomas

AU - Frejborg, Fanny

AU - Lund, Liisa M.

AU - Nyman, Marie C.

AU - Orpana, Julius

AU - Habib, Huda

AU - Alaollitervo, Salla

AU - Levanova, Alesia A.

AU - Poranen, Minna M.

AU - Hukkanen, Veijo

AU - Kalke, Kiira

PY - 2023/5/10

Y1 - 2023/5/10

UR - https://doi.org/10.1002/SMMD.20230009

U2 - 10.1002/SMMD.20230009

DO - 10.1002/SMMD.20230009

M3 - Article

SN - 2751-1871

JO - Smart Medicine

JF - Smart Medicine

M1 - e20230009

ER -

Single therapeutic dose of an antiviral UL29 siRNA swarm diminishes symptoms and viral load of mice infected intranasally with HSV‐1

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