Simulation of one dimensional staged DNA tile assembly by the signal-passing hierarchical TAM

Gefry Barad, Alexandru Amarioarei, Mihaela Paun, Ana Maria Dobre, Corina Itcus, Iris Tusa, Romica Trandafir, Eugen Czeizler

    Research output: Chapter in Book/Conference proceedingConference contributionScientificpeer-review

    2 Citations (Scopus)

    Abstract

    The Tile Assembly Model, and its many variants, is one of the most fundamental algorithmic assembly formalism within DNA nanotechnology. Most of the research in this field is focused on the complexity of assembling different shapes and patterns. In many cases, the assembly process is intrinsically deterministic and the final product is unique, while the assembly process might evolve through several possible assembly strategies. In this study we consider the controlled assembly of one dimensional tile structures according to predefined assembly graphs. We provide algorithmic approaches for developing such controlled assembly protocols, using the signal-passing Tile Assembly Model, as well as probabilistic approaches for investigating the assembly of such tile-based one-dimensional structures. As a byproduct, we build a generalized TAS (tile assembly system) which generate specific non-local non-associative algebraic computations and we assamble n × n squares using only one tile, which is a better efficiency compared to the staged assembly model.

    Original languageUndefined/Unknown
    Title of host publicationKnowledge-Based and Intelligent Information & Engineering Systems: Proceedings of the 23rd International Conference KES2019
    EditorsImre J. Rudas, Csirik Janos, Carlos Toro, Janos Botzheim, Robert J. Howlett, Lakhmi C. Jain
    PublisherElsevier
    Pages1918–1927
    DOIs
    Publication statusPublished - 2019
    MoE publication typeA4 Article in a conference publication
    EventKnowledge-Based and Intelligent Information & Engineering Systems - KES 2019 23rd International Conference on Knowledge-Based and Intelligent Information & Engineering Systems
    Duration: 4 Sep 20196 Sep 2019

    Conference

    ConferenceKnowledge-Based and Intelligent Information & Engineering Systems
    Period04/09/1906/09/19

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