SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland.

null Peuhu; null Kaukonen; null Lerche; null Saari; null Guzmán; null Rantakari; De Franceschi; null Wärri; null Georgiadou; Guillaume Jacquemet; null Mattila; null Virtakoivu; null Liu; null Attieh; null Silva; null Betz; null Sundberg; null Salmi; null Deugnier; null Eliceiri; null Ivaska

doi:10.15252/embj.201694387

SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland.

Peuhu, Kaukonen, Lerche, Saari, Guzmán, Rantakari, De Franceschi, Wärri, Georgiadou, Guillaume Jacquemet, Mattila, Virtakoivu, Liu, Attieh, Silva, Betz, Sundberg, Salmi, Deugnier, EliceiriIvaska

Research output: Contribution to journal › Article › Scientific › peer-review

35 Citations (Scopus)

Abstract

mammary gland stromal fibroblasts demonstrated defects in collagen fibre assembly, collagen contraction and degradation in vitro Together, these data imply that SHARPIN regulates the normal invasive mammary gland branching morphogenesis in an epithelial cell extrinsic manner by controlling the organisation of the stromal ECM.

Original language	Undefined/Unknown
Pages (from-to)	165–182
Journal	EMBO Journal
Volume	36
Issue number	2
DOIs	https://doi.org/10.15252/embj.201694387
Publication status	Published - 2017
MoE publication type	A1 Journal article-refereed

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10.15252/embj.201694387

Cite this

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title = "SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland.",

abstract = "mammary gland stromal fibroblasts demonstrated defects in collagen fibre assembly, collagen contraction and degradation in vitro Together, these data imply that SHARPIN regulates the normal invasive mammary gland branching morphogenesis in an epithelial cell extrinsic manner by controlling the organisation of the stromal ECM.",

author = "Peuhu and Kaukonen and Lerche and Saari and Guzm{\'a}n and Rantakari and De Franceschi and W{\"a}rri and Georgiadou and Guillaume Jacquemet and Mattila and Virtakoivu and Liu and Attieh and Silva and Betz and Sundberg and Salmi and Deugnier and Eliceiri and Ivaska",

year = "2017",

doi = "10.15252/embj.201694387",

language = "Odefinierat/ok{\"a}nt",

volume = "36",

pages = "165–182",

journal = "EMBO Journal",

issn = "0261-4189",

publisher = "EMBO Press",

number = "2",

}

Peuhu, Kaukonen, Lerche, Saari, Guzmán, Rantakari, Franceschi, D, Wärri, Georgiadou, , Jacquemet, G, Mattila, Virtakoivu, Liu, Attieh, Silva, Betz, Sundberg, Salmi, Deugnier, Eliceiri & Ivaska 2017, 'SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland.', EMBO Journal, vol. 36, no. 2, pp. 165–182. https://doi.org/10.15252/embj.201694387

TY - JOUR

T1 - SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland.

AU - Peuhu, null

AU - Kaukonen, null

AU - Lerche, null

AU - Saari, null

AU - Guzmán, null

AU - Rantakari, null

AU - Franceschi, De

AU - Wärri, null

AU - Georgiadou, null

AU - Jacquemet, Guillaume

AU - Mattila, null

AU - Virtakoivu, null

AU - Liu, null

AU - Attieh, null

AU - Silva, null

AU - Betz, null

AU - Sundberg, null

AU - Salmi, null

AU - Deugnier, null

AU - Eliceiri, null

AU - Ivaska, null

PY - 2017

Y1 - 2017

N2 - mammary gland stromal fibroblasts demonstrated defects in collagen fibre assembly, collagen contraction and degradation in vitro Together, these data imply that SHARPIN regulates the normal invasive mammary gland branching morphogenesis in an epithelial cell extrinsic manner by controlling the organisation of the stromal ECM.

AB - mammary gland stromal fibroblasts demonstrated defects in collagen fibre assembly, collagen contraction and degradation in vitro Together, these data imply that SHARPIN regulates the normal invasive mammary gland branching morphogenesis in an epithelial cell extrinsic manner by controlling the organisation of the stromal ECM.

U2 - 10.15252/embj.201694387

DO - 10.15252/embj.201694387

M3 - Artikel

SN - 0261-4189

VL - 36

SP - 165

EP - 182

JO - EMBO Journal

JF - EMBO Journal

IS - 2

ER -