Rhamnosylation of lignans by a Streptomyces strain

Patrik Christoffer Eklund; Toni Holmström; Lamis Al-Ubaydy; Rainer Sjöholm; Juha Hakala

doi:10.1016/j.tetlet.2005.12.107

Rhamnosylation of lignans by a Streptomyces strain

Patrik Christoffer Eklund
, Toni Holmström
, Lamis Al-Ubaydy
, Rainer Sjöholm
, Juha Hakala

Research output: Contribution to journal › Article › Scientific › peer-review

7 Citations (Scopus)

Abstract

Screening of 400 Streptomyces strains for biotransformation of the natural lignan matairesinol led to the identification of Streptomyces sp. LS136, capable of producing a single metabolite in moderate yields. Isolation and purification by preparative HPLC, followed by structural analyses by LC-MS and NMR, established the structure as matairesinol-4-O-rhamnoside. This bacterial strain was also used for rhamnosylation of the abundant natural lignans, hydroxymatairesinol and secoisolariciresinol. (c) 2006 Elsevier Ltd. All rights reserved.

Original language	Undefined/Unknown
Pages (from-to)	1645–1648
Number of pages	4
Journal	Tetrahedron Letters
Volume	47
Issue number	10
DOIs	https://doi.org/10.1016/j.tetlet.2005.12.107
Publication status	Published - 2006
MoE publication type	A1 Journal article-refereed

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10.1016/j.tetlet.2005.12.107

Cite this

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title = "Rhamnosylation of lignans by a Streptomyces strain",

abstract = "Screening of 400 Streptomyces strains for biotransformation of the natural lignan matairesinol led to the identification of Streptomyces sp. LS136, capable of producing a single metabolite in moderate yields. Isolation and purification by preparative HPLC, followed by structural analyses by LC-MS and NMR, established the structure as matairesinol-4-O-rhamnoside. This bacterial strain was also used for rhamnosylation of the abundant natural lignans, hydroxymatairesinol and secoisolariciresinol. (c) 2006 Elsevier Ltd. All rights reserved.",

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T1 - Rhamnosylation of lignans by a Streptomyces strain

AU - Eklund, Patrik Christoffer

AU - Holmström, Toni

AU - Al-Ubaydy, Lamis

AU - Sjöholm, Rainer

AU - Hakala, Juha

PY - 2006

Y1 - 2006

N2 - Screening of 400 Streptomyces strains for biotransformation of the natural lignan matairesinol led to the identification of Streptomyces sp. LS136, capable of producing a single metabolite in moderate yields. Isolation and purification by preparative HPLC, followed by structural analyses by LC-MS and NMR, established the structure as matairesinol-4-O-rhamnoside. This bacterial strain was also used for rhamnosylation of the abundant natural lignans, hydroxymatairesinol and secoisolariciresinol. (c) 2006 Elsevier Ltd. All rights reserved.

AB - Screening of 400 Streptomyces strains for biotransformation of the natural lignan matairesinol led to the identification of Streptomyces sp. LS136, capable of producing a single metabolite in moderate yields. Isolation and purification by preparative HPLC, followed by structural analyses by LC-MS and NMR, established the structure as matairesinol-4-O-rhamnoside. This bacterial strain was also used for rhamnosylation of the abundant natural lignans, hydroxymatairesinol and secoisolariciresinol. (c) 2006 Elsevier Ltd. All rights reserved.

U2 - 10.1016/j.tetlet.2005.12.107

DO - 10.1016/j.tetlet.2005.12.107

M3 - Artikel

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JO - Tetrahedron Letters

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