TY - JOUR
T1 - Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations
AU - Zafar, S
AU - Quarta, null
AU - Marradi, null
AU - Ragusa, null
PY - 2019/10/1
Y1 - 2019/10/1
N2 - Reactive oxygen and nitrogen species (RONS) are produced endogenously in our body, or introduced through external factors, such as pollution, cigarette smoke, and excessive sunlight exposure. In normal conditions, there is a physiological balance between pro-oxidant species and antioxidant molecules that are able to counteract the detrimental effect of the former. Nevertheless, when this homeostasis is disrupted, the resulting oxidative stress can lead to several pathological conditions, from inflammation to cancer and neurodegenerative diseases. In this review, we report on the recent developments of different polymeric formulations that are able to reduce the oxidative stress, from natural extracts, to films and hydrogels, and finally to nanoparticles (NPs)
AB - Reactive oxygen and nitrogen species (RONS) are produced endogenously in our body, or introduced through external factors, such as pollution, cigarette smoke, and excessive sunlight exposure. In normal conditions, there is a physiological balance between pro-oxidant species and antioxidant molecules that are able to counteract the detrimental effect of the former. Nevertheless, when this homeostasis is disrupted, the resulting oxidative stress can lead to several pathological conditions, from inflammation to cancer and neurodegenerative diseases. In this review, we report on the recent developments of different polymeric formulations that are able to reduce the oxidative stress, from natural extracts, to films and hydrogels, and finally to nanoparticles (NPs)
UR - http://dx.doi.org/10.3390/pharmaceutics11100505
U2 - 10.3390/pharmaceutics11100505
DO - 10.3390/pharmaceutics11100505
M3 - Article
SN - 1999-4923
JO - Pharmaceutics
JF - Pharmaceutics
ER -