Rapid, simple, and efficient deprotection of benzyl/benzylidene protected carbohydrates by utilization of flow chemistry

FS Ekholm, IM Mandity, F Fulop, Reko Leino

    Research output: Contribution to journalArticleScientificpeer-review

    14 Citations (Scopus)

    Abstract

    A rapid, simple, and efficient deprotection procedure for the deprotection of benzyl- and/or benzylidene protected carbohydrates is described utilizing a continuous flow hydrogenation reactor. The method tolerates both acid- and base sensitive functional groups. The high efficiency, simple work-up, and short reaction time should make this method appealing to researchers working in the fields of carbohydrate chemistry and total synthesis. (C) 2011 Elsevier Ltd. All rights reserved.
    Original languageUndefined/Unknown
    Pages (from-to)1839–1841
    Number of pages3
    JournalTetrahedron Letters
    Volume52
    Issue number16
    DOIs
    Publication statusPublished - 2011
    MoE publication typeA1 Journal article-refereed

    Keywords

    • Benzyl/benzylidene
    • Flow chemistry
    • Heterogenous catalysis
    • Protective groups

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