Abstract
We consider in this paper the modeling of biological systems
with guarded command models. We focus on the model refinement problem:
to systematically add details to the variables of a model and thus,
to dynamically specify a model at different levels of detail. We introduce
a notion of refinement for guarded command models and prove that it is
a natural extension of the model refinement concept for reaction-based
models. We demonstrate these concepts with a a running example on the
heat shock response.
Original language | Undefined/Unknown |
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Title of host publication | Multidisciplinary Creativity : homage to Gheorghe Pӑun on his 65th birthday |
Editors | Marian Gheorghe, Ion Petre, Mario J. Pérez-Jiménez, Grzegorz Rozenberg, Arto Salomaa |
Publisher | Spandugino |
Pages | 196–206 |
ISBN (Print) | 978-606-8401-63-8 |
Publication status | Published - 2015 |
MoE publication type | A3 Part of a book or another research book |