Printing technologies for biomolecule and cell-based applications

Petri Ihalainen, Anni Määttänen, Niklas Sandler

Research output: Contribution to journalReview Article or Literature Reviewpeer-review

30 Citations (Scopus)

Abstract

Biomolecules, such as enzymes, proteins and other biomacromolecules (polynucleotides, polypeptides, polysaccharides and DNA) that are immobilized on solid surfaces are relevant to many areas of science and technology. These functionalized surfaces have applications in biosensors, chromatography, diagnostic immunoassays, cell culturing, DNA microarrays and other analytical techniques. Printing technologies offer opportunities in this context. The main interests in printing biomolecules are in immobilizing them on surfaces for sensors and catalysts or for controlled delivery of protein-based drugs. Recently, there have been significant developments in the use of inkjet printing for dispensing of proteins, biomacromolecules and cells. This review discusses the use of roll-to-roll and inkjet printing technologies in manufacturing of biomolecule and cell-based applications.
Original languageUndefined/Unknown
Pages (from-to)585–592
JournalInternational Journal of Pharmaceutics
Volume494
Issue number2
DOIs
Publication statusPublished - 2015
MoE publication typeA2 Review article in a scientific journal

Keywords

  • Printing
  • Enzymes
  • Proteins
  • Biomacromolecules
  • Inkjet printing
  • Roll-to-roll printing
  • Flexographic printing
  • Biomolecules
  • cell

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