Polymeric iodophors with poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone): optical, hydrodynamic, thermodynamic, and antimicrobial properties

Danelya N. Makhayeva; Sergey K. Filippov; Sanzhar S. Yestemes; Galiya S. Irmukhametova; Vitaliy V. Khutoryanskiy

doi:10.1016/j.eurpolymj.2022.111005

Polymeric iodophors with poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone): optical, hydrodynamic, thermodynamic, and antimicrobial properties

Danelya N. Makhayeva
, Sergey K. Filippov
, Sanzhar S. Yestemes
, Galiya S. Irmukhametova
, Vitaliy V. Khutoryanskiy^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

13 Citations (Scopus)

254 Downloads (Pure)

Abstract

Formation of iodophors by interactions of poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone) with molecular iodine dissolved in aqueous solutions with addition of potassium iodide and ethanol has been studied using a range of physicochemical techniques including UV–Vis spectroscopy, viscometry, dynamic light scattering, isothermal titration calorimetry and partitioning through semi-permeable membrane. It was established that poly(2-ethyl-2-oxazoline) exhibits greater ability to bind iodine compared to poly(N-vinylpyrrolidone). Despite the difference in the binding ability of these two polymers, their iodophors exhibited similar antimicrobial properties.

Original language	English
Article number	111005
Journal	European Polymer Journal
Volume	165
DOIs	https://doi.org/10.1016/j.eurpolymj.2022.111005
Publication status	Published - 15 Feb 2022
MoE publication type	A1 Journal article-refereed

Funding

I.G.S. acknowledges Ministry of Education and Science of the Republic of Kazakhstan for the research grant (No. AP08052780). S.K.F. and V.V.K. acknowledge the Leverhulme Trust for the visiting professorship grant (VP2-2020-013) to support the visit and work of S.F.K. at the University of Reading. The authors also acknowledge Ardak Jumagaziyeva and Zhanar Iskakbayeva from Laboratory of Microbiology, Scientific Center of Anti-Infectious Drugs (SCAID, Almaty, Kazakhstan) for technical help with microbiological experiments. I.G.S. acknowledges Ministry of Education and Science of the Republic of Kazakhstan for the research grant (No. AP08052780). S.K.F. and V.V.K. acknowledge the Leverhulme Trust for the visiting professorship grant ( VP2-2020-013 ) to support the visit and work of S.F.K. at the University of Reading. The authors also acknowledge Ardak Jumagaziyeva and Zhanar Iskakbayeva from Laboratory of Microbiology, Scientific Center of Anti-Infectious Drugs (SCAID, Almaty, Kazakhstan) for technical help with microbiological experiments.

Keywords

Antimicrobial properties
Iodine
Iodophors
Poly(2-ethyl-2-oxazoline)
Poly(N-vinylpyrrolidone)
Polymers

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10.1016/j.eurpolymj.2022.111005

Polymeric iodophors with polyFinal published version, 3.82 MBLicence: CC BY

https://urn.fi/URN:NBN:fi-fe2023022228222

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@article{1a12c5efbd064bfd8d6a26b2a796e745,

title = "Polymeric iodophors with poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone): optical, hydrodynamic, thermodynamic, and antimicrobial properties",

abstract = "Formation of iodophors by interactions of poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone) with molecular iodine dissolved in aqueous solutions with addition of potassium iodide and ethanol has been studied using a range of physicochemical techniques including UV{\textendash}Vis spectroscopy, viscometry, dynamic light scattering, isothermal titration calorimetry and partitioning through semi-permeable membrane. It was established that poly(2-ethyl-2-oxazoline) exhibits greater ability to bind iodine compared to poly(N-vinylpyrrolidone). Despite the difference in the binding ability of these two polymers, their iodophors exhibited similar antimicrobial properties.",

keywords = "Antimicrobial properties, Iodine, Iodophors, Poly(2-ethyl-2-oxazoline), Poly(N-vinylpyrrolidone), Polymers",

author = "Makhayeva, \{Danelya N.\} and Filippov, \{Sergey K.\} and Yestemes, \{Sanzhar S.\} and Irmukhametova, \{Galiya S.\} and Khutoryanskiy, \{Vitaliy V.\}",

note = "Funding Information: I.G.S. acknowledges Ministry of Education and Science of the Republic of Kazakhstan for the research grant (No. AP08052780). S.K.F. and V.V.K. acknowledge the Leverhulme Trust for the visiting professorship grant (VP2-2020-013) to support the visit and work of S.F.K. at the University of Reading. The authors also acknowledge Ardak Jumagaziyeva and Zhanar Iskakbayeva from Laboratory of Microbiology, Scientific Center of Anti-Infectious Drugs (SCAID, Almaty, Kazakhstan) for technical help with microbiological experiments. Funding Information: I.G.S. acknowledges Ministry of Education and Science of the Republic of Kazakhstan for the research grant (No. AP08052780). S.K.F. and V.V.K. acknowledge the Leverhulme Trust for the visiting professorship grant ( VP2-2020-013 ) to support the visit and work of S.F.K. at the University of Reading. The authors also acknowledge Ardak Jumagaziyeva and Zhanar Iskakbayeva from Laboratory of Microbiology, Scientific Center of Anti-Infectious Drugs (SCAID, Almaty, Kazakhstan) for technical help with microbiological experiments. Publisher Copyright: {\textcopyright} 2022 Elsevier Ltd",

year = "2022",

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day = "15",

doi = "10.1016/j.eurpolymj.2022.111005",

language = "English",

volume = "165",

journal = "European Polymer Journal",

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T1 - Polymeric iodophors with poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone)

T2 - optical, hydrodynamic, thermodynamic, and antimicrobial properties

AU - Makhayeva, Danelya N.

AU - Filippov, Sergey K.

AU - Yestemes, Sanzhar S.

AU - Irmukhametova, Galiya S.

AU - Khutoryanskiy, Vitaliy V.

N1 - Funding Information: I.G.S. acknowledges Ministry of Education and Science of the Republic of Kazakhstan for the research grant (No. AP08052780). S.K.F. and V.V.K. acknowledge the Leverhulme Trust for the visiting professorship grant (VP2-2020-013) to support the visit and work of S.F.K. at the University of Reading. The authors also acknowledge Ardak Jumagaziyeva and Zhanar Iskakbayeva from Laboratory of Microbiology, Scientific Center of Anti-Infectious Drugs (SCAID, Almaty, Kazakhstan) for technical help with microbiological experiments. Funding Information: I.G.S. acknowledges Ministry of Education and Science of the Republic of Kazakhstan for the research grant (No. AP08052780). S.K.F. and V.V.K. acknowledge the Leverhulme Trust for the visiting professorship grant ( VP2-2020-013 ) to support the visit and work of S.F.K. at the University of Reading. The authors also acknowledge Ardak Jumagaziyeva and Zhanar Iskakbayeva from Laboratory of Microbiology, Scientific Center of Anti-Infectious Drugs (SCAID, Almaty, Kazakhstan) for technical help with microbiological experiments. Publisher Copyright: © 2022 Elsevier Ltd

PY - 2022/2/15

Y1 - 2022/2/15

N2 - Formation of iodophors by interactions of poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone) with molecular iodine dissolved in aqueous solutions with addition of potassium iodide and ethanol has been studied using a range of physicochemical techniques including UV–Vis spectroscopy, viscometry, dynamic light scattering, isothermal titration calorimetry and partitioning through semi-permeable membrane. It was established that poly(2-ethyl-2-oxazoline) exhibits greater ability to bind iodine compared to poly(N-vinylpyrrolidone). Despite the difference in the binding ability of these two polymers, their iodophors exhibited similar antimicrobial properties.

AB - Formation of iodophors by interactions of poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone) with molecular iodine dissolved in aqueous solutions with addition of potassium iodide and ethanol has been studied using a range of physicochemical techniques including UV–Vis spectroscopy, viscometry, dynamic light scattering, isothermal titration calorimetry and partitioning through semi-permeable membrane. It was established that poly(2-ethyl-2-oxazoline) exhibits greater ability to bind iodine compared to poly(N-vinylpyrrolidone). Despite the difference in the binding ability of these two polymers, their iodophors exhibited similar antimicrobial properties.

KW - Antimicrobial properties

KW - Iodine

KW - Iodophors

KW - Poly(2-ethyl-2-oxazoline)

KW - Poly(N-vinylpyrrolidone)

KW - Polymers

UR - https://www.scopus.com/pages/publications/85123045987

U2 - 10.1016/j.eurpolymj.2022.111005

DO - 10.1016/j.eurpolymj.2022.111005

M3 - Article

AN - SCOPUS:85123045987

SN - 0014-3057

VL - 165

JO - European Polymer Journal

JF - European Polymer Journal

M1 - 111005

ER -

Polymeric iodophors with poly(2-ethyl-2-oxazoline) and poly(N-vinylpyrrolidone): optical, hydrodynamic, thermodynamic, and antimicrobial properties

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Keywords

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