Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells

Niina M. Santio; Sebastian K.-J. Landor; Laura Vahtera; Jani Ylä-Pelto; Elina Paloniemi; Susumu Imanishi; Garry Corthals; Markku Varjosalo; Ganesh Babu Manoharan; Asko Uri; Urban Lendahl; Cecilia Sahlgren; Päivi J. Koskinen

doi:10.18632/oncotarget.9215

Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells

Niina M. Santio, Sebastian K.-J. Landor, Laura Vahtera, Jani Ylä-Pelto, Elina Paloniemi, Susumu Imanishi, Garry Corthals, Markku Varjosalo, Ganesh Babu Manoharan, Asko Uri, Urban Lendahl, Cecilia Sahlgren, Päivi J. Koskinen

Research output: Contribution to journal › Article › Scientific › peer-review

53 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	43220–43238
Journal	Oncotarget
Volume	7
Issue number	28
DOIs	https://doi.org/10.18632/oncotarget.9215
Publication status	Published - 2016
MoE publication type	A1 Journal article-refereed

Funding

This work was supported by the Academy of Finland grants 121533, 287040 (PJK), 218062 (CS) and 128712 (GC), Sigrid Juselius Foundation and Cancer Society of Finland (CS), the Estonian Research Council grant IUT20-17 (AU, GM), the European Social Fund's Doctoral Studies Programme DoRa through the Archimedes Foundation (GM), Drug Research Doctoral Programme (NMS, JYP), Emil Aaltonen Foundation, Cancer Organizations for the Western Finland, Orion-Farmos Research Foundation, Finnish Cultural Foundation, Cancer Society of Finland/the Finnish Cancer Organisations and Turku University Foundation (NMS), Swedish Cultural Foundation of Finland, Magnus Ehrnrooth Foundation, Waldemar von Frenckell Foundation, K. Albin Johansson Foundation, Liv och Hälsa Foundation, Knut and Alice Wallenberg Foundation, the Swedish Cancer Society, the Swedish Research Council, EU (ITN NotchIT) and Karolinska Institutet (BRECT Theme Center) (SKJL, UL).

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10.18632/oncotarget.9215

Targeting Notch signalign in cancer
Sahlgren, C. (Principal Investigator)
01/01/10 → 31/07/14
Project: Research

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Santio, N. M., Landor, S. K.-J., Vahtera, L., Ylä-Pelto, J., Paloniemi, E., Imanishi, S., Corthals, G., Varjosalo, M., Babu Manoharan, G., Uri, A., Lendahl, U., Sahlgren, C., & Koskinen, P. J. (2016). Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells. Oncotarget, 7(28), 43220–43238. https://doi.org/10.18632/oncotarget.9215

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title = "Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells",

author = "Santio, \{Niina M.\} and Landor, \{Sebastian K.-J.\} and Laura Vahtera and Jani Yl{\"a}-Pelto and Elina Paloniemi and Susumu Imanishi and Garry Corthals and Markku Varjosalo and \{Babu Manoharan\}, Ganesh and Asko Uri and Urban Lendahl and Cecilia Sahlgren and Koskinen, \{P{\"a}ivi J.\}",

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doi = "10.18632/oncotarget.9215",

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number = "28",

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Santio, NM, Landor, SK-J, Vahtera, L, Ylä-Pelto, J, Paloniemi, E, Imanishi, S, Corthals, G, Varjosalo, M, Babu Manoharan, G, Uri, A, Lendahl, U, Sahlgren, C & Koskinen, PJ 2016, 'Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells', Oncotarget, vol. 7, no. 28, pp. 43220–43238. https://doi.org/10.18632/oncotarget.9215

TY - JOUR

T1 - Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells

AU - Santio, Niina M.

AU - Landor, Sebastian K.-J.

AU - Vahtera, Laura

AU - Ylä-Pelto, Jani

AU - Paloniemi, Elina

AU - Imanishi, Susumu

AU - Corthals, Garry

AU - Varjosalo, Markku

AU - Babu Manoharan, Ganesh

AU - Uri, Asko

AU - Lendahl, Urban

AU - Sahlgren, Cecilia

AU - Koskinen, Päivi J.

PY - 2016

Y1 - 2016

U2 - 10.18632/oncotarget.9215

DO - 10.18632/oncotarget.9215

M3 - Artikel

SN - 1949-2553

VL - 7

SP - 43220

EP - 43238

JO - Oncotarget

JF - Oncotarget

IS - 28

ER -

Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells

Funding

Access to Document

Projects

Targeting Notch signalign in cancer

Cite this