Perspectives of Printing Technologies in Continuous Drug Manufacturing

Niklas Sandler, Petri Ihalainen

Research output: Chapter in Book/Conference proceedingChapterScientific

Abstract

This chapter discusses and gives future perspectives of the use of printing technologies in the manufacture of drugs. It describes the following techniques: inkjet printing (drop deposition); flexographic printing; and fused filament deposition. The promising advancements in printing technologies support dose personalization development in the pharmaceutical industry and can contribute to attractive options for continuous manufacturing. Reliable and robust methods for the quality control of created formulations are needed if printing becomes a viable option in point of care applications. Most application examples in the chapter deal with desktop flexography and research-scale inkjet models that are available for drug delivery system prototype fabrication for accurate dosing, multi-dosing, and material deposition in general. Due to the varying nature of inks and the complexity in the structures to be produced, single printing methods cannot meet all the needs required in fabricating complex multilayer and composite (multi-component) structures.

Original languageUndefined/Unknown
Title of host publicationContinuous Manufacturing of Pharmaceuticals
EditorsPeter Kleinebudde, Johannes Khinast, Jukka Rantanen
PublisherJohn Wiley & Sons
Pages525–549
ISBN (Electronic)9781119001348
ISBN (Print)9781119001324
DOIs
Publication statusPublished - 2017
MoE publication typeB2 Part of a book or another research book

Keywords

  • 3D printing
  • Continuous drug manufacturing
  • Drug delivery systems
  • Flexographic printing
  • Fused filament deposition
  • Inkjet printing
  • Pharmaceutical industry
  • Quality control

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