Oxyethylene chain-cation complexation; Nonionic polyoxyethylene detergents attain a positive charge and demonstrate electrostatic head group interactions

H Hagerstrand; Johan Bobacka; M Bobrowska-Hagerstrand; V Kralj-Iglic; M Fosnaric; A Iglic

Oxyethylene chain-cation complexation; Nonionic polyoxyethylene detergents attain a positive charge and demonstrate electrostatic head group interactions

H Hagerstrand, Johan Bobacka, M Bobrowska-Hagerstrand, V Kralj-Iglic, M Fosnaric, A Iglic

Laboratory of Molecular Science and Engineering

Research output: Contribution to journal › Article › Scientific › peer-review

21 Citations (Scopus)

Abstract

We report literature data indicating that the polyoxyethylene chain of polyoxyethylene detergents attracts cations via dipole-ion interactions thereby attaining a positive charge character. This implies that nonionic polyoxyethylene detergents like Triton X-100 and C12E8 may interact electrostatically with phospholipid head groups. We describe how a positive charge character of Triton X-100 and C12E8 can explain their hitherto mysterious stomatocytogenic shape altering effect in human erythrocytes.

Original language	Undefined/Unknown
Pages (from-to)	161–165
Number of pages	5
Journal	Cellular and Molecular Biology Letters
Volume	6
Publication status	Published - 2001
MoE publication type	A1 Journal article-refereed

Keywords

erythrocyte membrane
shape change
CmEn
PEG
polyoxyethylene
Triton X-100

Cite this

@article{b5801185306c493f9c4f8053948c7dd4,

title = "Oxyethylene chain-cation complexation; Nonionic polyoxyethylene detergents attain a positive charge and demonstrate electrostatic head group interactions",

abstract = "We report literature data indicating that the polyoxyethylene chain of polyoxyethylene detergents attracts cations via dipole-ion interactions thereby attaining a positive charge character. This implies that nonionic polyoxyethylene detergents like Triton X-100 and C12E8 may interact electrostatically with phospholipid head groups. We describe how a positive charge character of Triton X-100 and C12E8 can explain their hitherto mysterious stomatocytogenic shape altering effect in human erythrocytes.",

keywords = "erythrocyte membrane, shape change, CmEn, PEG, polyoxyethylene, Triton X-100, erythrocyte membrane, shape change, CmEn, PEG, polyoxyethylene, Triton X-100, erythrocyte membrane, shape change, CmEn, PEG, polyoxyethylene, Triton X-100",

author = "H Hagerstrand and Johan Bobacka and M Bobrowska-Hagerstrand and V Kralj-Iglic and M Fosnaric and A Iglic",

year = "2001",

language = "Odefinierat/ok{\"a}nt",

volume = "6",

pages = "161–165",

journal = "Cellular and Molecular Biology Letters",

issn = "1425-8153",

}

Oxyethylene chain-cation complexation; Nonionic polyoxyethylene detergents attain a positive charge and demonstrate electrostatic head group interactions. / Hagerstrand, H; Bobacka, Johan; Bobrowska-Hagerstrand, M et al.
In: Cellular and Molecular Biology Letters, Vol. 6, 2001, p. 161–165.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Oxyethylene chain-cation complexation; Nonionic polyoxyethylene detergents attain a positive charge and demonstrate electrostatic head group interactions

AU - Hagerstrand, H

AU - Bobacka, Johan

AU - Bobrowska-Hagerstrand, M

AU - Kralj-Iglic, V

AU - Fosnaric, M

AU - Iglic, A

PY - 2001

Y1 - 2001

N2 - We report literature data indicating that the polyoxyethylene chain of polyoxyethylene detergents attracts cations via dipole-ion interactions thereby attaining a positive charge character. This implies that nonionic polyoxyethylene detergents like Triton X-100 and C12E8 may interact electrostatically with phospholipid head groups. We describe how a positive charge character of Triton X-100 and C12E8 can explain their hitherto mysterious stomatocytogenic shape altering effect in human erythrocytes.

AB - We report literature data indicating that the polyoxyethylene chain of polyoxyethylene detergents attracts cations via dipole-ion interactions thereby attaining a positive charge character. This implies that nonionic polyoxyethylene detergents like Triton X-100 and C12E8 may interact electrostatically with phospholipid head groups. We describe how a positive charge character of Triton X-100 and C12E8 can explain their hitherto mysterious stomatocytogenic shape altering effect in human erythrocytes.

KW - erythrocyte membrane

KW - shape change

KW - CmEn

KW - PEG

KW - polyoxyethylene

KW - Triton X-100

KW - erythrocyte membrane

KW - shape change

KW - CmEn

KW - PEG

KW - polyoxyethylene

KW - Triton X-100

KW - erythrocyte membrane

KW - shape change

KW - CmEn

KW - PEG

KW - polyoxyethylene

KW - Triton X-100

M3 - Artikel

SN - 1425-8153

VL - 6

SP - 161

EP - 165

JO - Cellular and Molecular Biology Letters

JF - Cellular and Molecular Biology Letters

ER -