Nuclear stress granules: the awakening of a sleeping beauty?

A Sandqvist, Lea Sistonen

    Research output: Contribution to journalArticleScientificpeer-review

    17 Citations (Scopus)

    Abstract

    Nuclear stress granules are subnuclear compartments that form in response to heat shock and other stress stimuli. Although many components of nuclear stress granules have been identified, including HSF1 and pre-mRNA processing factors, their function remains a mystery. A paper in this issue describes the stress-induced transcriptional activation of one of the nuclear stress granule target sites, a heterochromatic region that has been considered silent (jolly et al., 2004). These intriguing findings will certainly give the research of these structures a new twist.
    Original languageUndefined/Unknown
    Pages (from-to)15–17
    Number of pages3
    JournalJournal of Cell Biology
    Volume164
    Issue number1
    Publication statusPublished - 2004
    MoE publication typeA1 Journal article-refereed

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