Novel plasma protein binding analysis method for a PET tracer and its radiometabolites: A case study with [C-11]SMW139 to explain the high uptake of radiometabolites in mouse brain

R Aarnio, OM Alzghool, S Wahlroos, J O'Brien-Brown, M Kassiou, O Solin, JO Rinne, S Forsback, M Haaparanta-Solin

Research output: Contribution to journalArticleScientificpeer-review

2 Citations (Scopus)
Original languageEnglish
Article number114860
Number of pages9
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume219
DOIs
Publication statusPublished - 20 Sep 2022
MoE publication typeA1 Journal article-refereed

Keywords

  • Parent fraction
  • Plasma protein binding
  • Positron emission tomography
  • RadioTLC
  • Radiometabolite analysis
  • Ultrafiltration
  • [C-11]SMW139

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