Neural signatures for active maintenance and interference during working memory updating

Adrià Vilà-Balló; Juha Salmitaival; Anna Soveri; Antoni Rodríguez-Fornells; Minna Lehtonen; Matti Laine

doi:10.1016/j.biopsycho.2018.01.007

Neural signatures for active maintenance and interference during working memory updating

Adrià Vilà-Balló, Juha Salmitaival, Anna Soveri, Antoni Rodríguez-Fornells, Minna Lehtonen, Matti Laine

Research output: Contribution to journal › Article › Scientific › peer-review

26 Citations (Scopus)

Abstract

Although working memory (WM) is amongst the most studied neurocognitive functions, temporal patterns of its component processes are not fully understood. We examined the neural underpinnings of active maintenance and interference management in the n-back task by manipulating load (1-back vs 3-back) and including so-called lure stimuli. ERPs of 27 young adults revealed that the 1-back condition enabling active maintenance showed a positive slow wave (PSW) prior to the next stimulus (-600-0 ms) and augmented P2 (190-290 ms) and P3b (330-430 ms) responses after the stimulus appeared, albeit the latter effects were driven by the initial PSW. Moreover, PSW amplitude correlated negatively with reaction time in the 1-back condition. Responses to lures showed interference, accompanied with different ERP effects for the two load levels. Our results support the view that PSW reflects efficient WM maintenance and suggest two distinct neuronal correlates for interference in WM.

Original language	Undefined/Unknown
Pages (from-to)	233–243
Journal	Biological Psychology
Volume	132
DOIs	https://doi.org/10.1016/j.biopsycho.2018.01.007
Publication status	Published - 2018
MoE publication type	A1 Journal article-refereed

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10.1016/j.biopsycho.2018.01.007

https://doi.org/10.1016/j.biopsycho.2018.01.007

Cite this

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title = "Neural signatures for active maintenance and interference during working memory updating",

abstract = "Although working memory (WM) is amongst the most studied neurocognitive functions, temporal patterns of its component processes are not fully understood. We examined the neural underpinnings of active maintenance and interference management in the n-back task by manipulating load (1-back vs 3-back) and including so-called lure stimuli. ERPs of 27 young adults revealed that the 1-back condition enabling active maintenance showed a positive slow wave (PSW) prior to the next stimulus (-600-0 ms) and augmented P2 (190-290 ms) and P3b (330-430 ms) responses after the stimulus appeared, albeit the latter effects were driven by the initial PSW. Moreover, PSW amplitude correlated negatively with reaction time in the 1-back condition. Responses to lures showed interference, accompanied with different ERP effects for the two load levels. Our results support the view that PSW reflects efficient WM maintenance and suggest two distinct neuronal correlates for interference in WM.",

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T1 - Neural signatures for active maintenance and interference during working memory updating

AU - Vilà-Balló, Adrià

AU - Salmitaival, Juha

AU - Soveri, Anna

AU - Rodríguez-Fornells, Antoni

AU - Lehtonen, Minna

AU - Laine, Matti

PY - 2018

Y1 - 2018

N2 - Although working memory (WM) is amongst the most studied neurocognitive functions, temporal patterns of its component processes are not fully understood. We examined the neural underpinnings of active maintenance and interference management in the n-back task by manipulating load (1-back vs 3-back) and including so-called lure stimuli. ERPs of 27 young adults revealed that the 1-back condition enabling active maintenance showed a positive slow wave (PSW) prior to the next stimulus (-600-0 ms) and augmented P2 (190-290 ms) and P3b (330-430 ms) responses after the stimulus appeared, albeit the latter effects were driven by the initial PSW. Moreover, PSW amplitude correlated negatively with reaction time in the 1-back condition. Responses to lures showed interference, accompanied with different ERP effects for the two load levels. Our results support the view that PSW reflects efficient WM maintenance and suggest two distinct neuronal correlates for interference in WM.

AB - Although working memory (WM) is amongst the most studied neurocognitive functions, temporal patterns of its component processes are not fully understood. We examined the neural underpinnings of active maintenance and interference management in the n-back task by manipulating load (1-back vs 3-back) and including so-called lure stimuli. ERPs of 27 young adults revealed that the 1-back condition enabling active maintenance showed a positive slow wave (PSW) prior to the next stimulus (-600-0 ms) and augmented P2 (190-290 ms) and P3b (330-430 ms) responses after the stimulus appeared, albeit the latter effects were driven by the initial PSW. Moreover, PSW amplitude correlated negatively with reaction time in the 1-back condition. Responses to lures showed interference, accompanied with different ERP effects for the two load levels. Our results support the view that PSW reflects efficient WM maintenance and suggest two distinct neuronal correlates for interference in WM.

U2 - 10.1016/j.biopsycho.2018.01.007

DO - 10.1016/j.biopsycho.2018.01.007

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JO - Biological Psychology

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