Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength

Damiano Verardo; Frida W. Lindberg; Nicklas Anttu; Cassandra S. Niman; Mercy Lard; Aleksandra P. Dabkowska; Tommy Nylander; Alf Månsson; Christelle N. Prinz; Heiner Linke

doi:10.1021/acs.nanolett.8b01360

Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength

Damiano Verardo
, Frida W. Lindberg
, Nicklas Anttu
, Cassandra S. Niman
, Mercy Lard
, Aleksandra P. Dabkowska
, Tommy Nylander
, Alf Månsson
, Christelle N. Prinz
, Heiner Linke^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

42 Citations (Scopus)

Abstract

Semiconductor nanowires can act as nanoscaled optical fibers, enabling them to guide and concentrate light emitted by surface-bound fluorophores, potentially enhancing the sensitivity of optical biosensing. While parameters such as the nanowire geometry and the fluorophore wavelength can be expected to strongly influence this lightguiding effect, no detailed description of their effect on in-coupling of fluorescent emission is available to date. Here, we use confocal imaging to quantify the lightguiding effect in GaP nanowires as a function of nanowire geometry and light wavelength. Using a combination of finite-difference time-domain simulations and analytical approaches, we identify the role of multiple waveguide modes for the observed lightguiding. The normalized frequency parameter, based on the step-index approximation, predicts the lightguiding ability of the nanowires as a function of diameter and fluorophore wavelength, providing a useful guide for the design of optical biosensors based on nanowires.

Original language	English
Pages (from-to)	4796-4802
Number of pages	7
Journal	Nano Letters
Volume	18
Issue number	8
DOIs	https://doi.org/10.1021/acs.nanolett.8b01360
Publication status	Published - 2018
Externally published	Yes
MoE publication type	A1 Journal article-refereed

Funding

We thank Dr. Steve Limpert for his help with the use of FDTD solutions. For financial support, we thank NanoLund, the Swedish Research Council (project number 2015-0612), the European Union’s Seventh Framework Programme (PhD4Energy, grant agreement no. 608153), the Horizon 2020 Research and Innovation Framework Programme of the European Union (Bio4Comp, grant agreement 732482, and NanoPokers, grant agreement no. 682206), and the Crafoord Foundation.

Keywords

biosensing
confocal microscopy
fluorescence
III-V
Nanowires
waveguiding

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10.1021/acs.nanolett.8b01360

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title = "Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength",

abstract = "Semiconductor nanowires can act as nanoscaled optical fibers, enabling them to guide and concentrate light emitted by surface-bound fluorophores, potentially enhancing the sensitivity of optical biosensing. While parameters such as the nanowire geometry and the fluorophore wavelength can be expected to strongly influence this lightguiding effect, no detailed description of their effect on in-coupling of fluorescent emission is available to date. Here, we use confocal imaging to quantify the lightguiding effect in GaP nanowires as a function of nanowire geometry and light wavelength. Using a combination of finite-difference time-domain simulations and analytical approaches, we identify the role of multiple waveguide modes for the observed lightguiding. The normalized frequency parameter, based on the step-index approximation, predicts the lightguiding ability of the nanowires as a function of diameter and fluorophore wavelength, providing a useful guide for the design of optical biosensors based on nanowires.",

keywords = "biosensing, confocal microscopy, fluorescence, III-V, Nanowires, waveguiding",

author = "Damiano Verardo and Lindberg, \{Frida W.\} and Nicklas Anttu and Niman, \{Cassandra S.\} and Mercy Lard and Dabkowska, \{Aleksandra P.\} and Tommy Nylander and Alf M{\aa}nsson and Prinz, \{Christelle N.\} and Heiner Linke",

note = "Publisher Copyright: Copyright {\textcopyright} 2018 American Chemical Society.",

year = "2018",

doi = "10.1021/acs.nanolett.8b01360",

language = "English",

volume = "18",

pages = "4796--4802",

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T2 - Lightguiding of Fluorescence as a Function of Diameter and Wavelength

AU - Verardo, Damiano

AU - Lindberg, Frida W.

AU - Anttu, Nicklas

AU - Niman, Cassandra S.

AU - Lard, Mercy

AU - Dabkowska, Aleksandra P.

AU - Nylander, Tommy

AU - Månsson, Alf

AU - Prinz, Christelle N.

AU - Linke, Heiner

PY - 2018

Y1 - 2018

N2 - Semiconductor nanowires can act as nanoscaled optical fibers, enabling them to guide and concentrate light emitted by surface-bound fluorophores, potentially enhancing the sensitivity of optical biosensing. While parameters such as the nanowire geometry and the fluorophore wavelength can be expected to strongly influence this lightguiding effect, no detailed description of their effect on in-coupling of fluorescent emission is available to date. Here, we use confocal imaging to quantify the lightguiding effect in GaP nanowires as a function of nanowire geometry and light wavelength. Using a combination of finite-difference time-domain simulations and analytical approaches, we identify the role of multiple waveguide modes for the observed lightguiding. The normalized frequency parameter, based on the step-index approximation, predicts the lightguiding ability of the nanowires as a function of diameter and fluorophore wavelength, providing a useful guide for the design of optical biosensors based on nanowires.

AB - Semiconductor nanowires can act as nanoscaled optical fibers, enabling them to guide and concentrate light emitted by surface-bound fluorophores, potentially enhancing the sensitivity of optical biosensing. While parameters such as the nanowire geometry and the fluorophore wavelength can be expected to strongly influence this lightguiding effect, no detailed description of their effect on in-coupling of fluorescent emission is available to date. Here, we use confocal imaging to quantify the lightguiding effect in GaP nanowires as a function of nanowire geometry and light wavelength. Using a combination of finite-difference time-domain simulations and analytical approaches, we identify the role of multiple waveguide modes for the observed lightguiding. The normalized frequency parameter, based on the step-index approximation, predicts the lightguiding ability of the nanowires as a function of diameter and fluorophore wavelength, providing a useful guide for the design of optical biosensors based on nanowires.

KW - biosensing

KW - confocal microscopy

KW - fluorescence

KW - III-V

KW - Nanowires

KW - waveguiding

UR - https://www.scopus.com/pages/publications/85049998667

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DO - 10.1021/acs.nanolett.8b01360

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SN - 1530-6984

VL - 18

SP - 4796

EP - 4802

JO - Nano Letters

JF - Nano Letters

IS - 8

ER -

Nanowires for Biosensing: Lightguiding of Fluorescence as a Function of Diameter and Wavelength

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Keywords

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