Nanodiamond based complexes for prolonged dexamethasone release

KA Laptinskiy, Helene Kettiger, OA Shenderova, SA Burikov, Jessica Rosenholm, TA Dolenko

Research output: Chapter in Book/Conference proceedingConference contributionScientificpeer-review

1 Citation (Scopus)

Abstract

In the article for the first time the properties of nanodiamond complexes with dexamethasone obtained by two different approaches - attachment of the drug to the surface of nanodiamond and to the nanodiamond, covered by silica layer – were compared. It was found that the synthesized nanocomposite ND@silica@Dex is able to retain a greater amount of drug and allows achieving prolonged release of dexamethasone. These properties of the complexes ND@silica@Dex provide prospects for their use as drug carries.

Original languageUndefined/Unknown
Title of host publicationSaratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions
EditorsDmitry Engelevich Postnov
PublisherSociety of Photo-Optical Instrumentation Engineers (SPIE)
Pages
ISBN (Print)9781510628243
DOIs
Publication statusPublished - 2019
MoE publication typeA4 Article in a conference publication
EventInternational Symposium on Optics and Biophotonics - INTERNATIONAL SYMPOSIUM ON OPTICS AND BIOPHOTONICS VI: SARATOV FALL MEETING 2018
Duration: 24 Sep 201829 Sep 2018

Conference

ConferenceInternational Symposium on Optics and Biophotonics
Period24/09/1829/09/18

Keywords

  • nanodiamonds

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