Nanodiamond based complexes for prolonged dexamethasone release

KA Laptinskiy; Helene Kettiger; OA Shenderova; SA Burikov; Jessica Rosenholm; TA Dolenko

doi:10.1117/12.2523336

Nanodiamond based complexes for prolonged dexamethasone release

KA Laptinskiy, Helene Kettiger, OA Shenderova, SA Burikov, Jessica Rosenholm, TA Dolenko

Research output: Chapter in Book/Conference proceeding › Conference contribution › Scientific › peer-review

2 Citations (Scopus)

Abstract

In the article for the first time the properties of nanodiamond complexes with dexamethasone obtained by two different approaches - attachment of the drug to the surface of nanodiamond and to the nanodiamond, covered by silica layer – were compared. It was found that the synthesized nanocomposite ND@silica@Dex is able to retain a greater amount of drug and allows achieving prolonged release of dexamethasone. These properties of the complexes ND@silica@Dex provide prospects for their use as drug carries.

Original language	Undefined/Unknown
Title of host publication	Saratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions
Editors	Dmitry Engelevich Postnov
Publisher	Society of Photo-Optical Instrumentation Engineers (SPIE)
Pages	–
ISBN (Print)	9781510628243
DOIs	https://doi.org/10.1117/12.2523336
Publication status	Published - 2019
MoE publication type	A4 Article in a conference publication
Event	International Symposium on Optics and Biophotonics - INTERNATIONAL SYMPOSIUM ON OPTICS AND BIOPHOTONICS VI: SARATOV FALL MEETING 2018 Duration: 24 Sept 2018 → 29 Sept 2018

Conference

Conference	International Symposium on Optics and Biophotonics
Period	24/09/18 → 29/09/18

Keywords

nanodiamonds

Access to Document

10.1117/12.2523336

https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11067/110671G/Nanodiamond-based-complexes-for-prolonged-dexamethasone-release/10.1117/12.2523336.short

Cite this

Laptinskiy, KA., Kettiger, H., Shenderova, OA., Burikov, SA., Rosenholm, J., & Dolenko, TA. (2019). Nanodiamond based complexes for prolonged dexamethasone release. In D. Engelevich Postnov (Ed.), Saratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions (pp. –). Society of Photo-Optical Instrumentation Engineers (SPIE). https://doi.org/10.1117/12.2523336

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title = "Nanodiamond based complexes for prolonged dexamethasone release",

abstract = "In the article for the first time the properties of nanodiamond complexes with dexamethasone obtained by two different approaches - attachment of the drug to the surface of nanodiamond and to the nanodiamond, covered by silica layer – were compared. It was found that the synthesized nanocomposite ND@silica@Dex is able to retain a greater amount of drug and allows achieving prolonged release of dexamethasone. These properties of the complexes ND@silica@Dex provide prospects for their use as drug carries.",

keywords = "nanodiamonds, nanodiamonds, nanodiamonds",

author = "KA Laptinskiy and Helene Kettiger and OA Shenderova and SA Burikov and Jessica Rosenholm and TA Dolenko",

year = "2019",

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booktitle = "Saratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions",

publisher = "Society of Photo-Optical Instrumentation Engineers (SPIE)",

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Laptinskiy, KA, Kettiger, H, Shenderova, OA, Burikov, SA, Rosenholm, J & Dolenko, TA 2019, Nanodiamond based complexes for prolonged dexamethasone release. in D Engelevich Postnov (ed.), Saratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions. Society of Photo-Optical Instrumentation Engineers (SPIE), pp. –, International Symposium on Optics and Biophotonics, 24/09/18. https://doi.org/10.1117/12.2523336

Nanodiamond based complexes for prolonged dexamethasone release. / Laptinskiy, KA; Kettiger, Helene; Shenderova, OA et al.
Saratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions. ed. / Dmitry Engelevich Postnov. Society of Photo-Optical Instrumentation Engineers (SPIE), 2019. p. –.

Research output: Chapter in Book/Conference proceeding › Conference contribution › Scientific › peer-review

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T1 - Nanodiamond based complexes for prolonged dexamethasone release

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AU - Kettiger, Helene

AU - Shenderova, OA

AU - Burikov, SA

AU - Rosenholm, Jessica

AU - Dolenko, TA

PY - 2019

Y1 - 2019

N2 - In the article for the first time the properties of nanodiamond complexes with dexamethasone obtained by two different approaches - attachment of the drug to the surface of nanodiamond and to the nanodiamond, covered by silica layer – were compared. It was found that the synthesized nanocomposite ND@silica@Dex is able to retain a greater amount of drug and allows achieving prolonged release of dexamethasone. These properties of the complexes ND@silica@Dex provide prospects for their use as drug carries.

AB - In the article for the first time the properties of nanodiamond complexes with dexamethasone obtained by two different approaches - attachment of the drug to the surface of nanodiamond and to the nanodiamond, covered by silica layer – were compared. It was found that the synthesized nanocomposite ND@silica@Dex is able to retain a greater amount of drug and allows achieving prolonged release of dexamethasone. These properties of the complexes ND@silica@Dex provide prospects for their use as drug carries.

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BT - Saratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions

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Laptinskiy KA, Kettiger H, Shenderova OA, Burikov SA, Rosenholm J, Dolenko TA. Nanodiamond based complexes for prolonged dexamethasone release. In Engelevich Postnov D, editor, Saratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions. Society of Photo-Optical Instrumentation Engineers (SPIE). 2019. p. – doi: 10.1117/12.2523336