Microcystin uptake inhibits growth and protein phosphatase activity in mustard (Sinapis alba L.) seedlings

Katriina Kurki-Helasmo, Jussi Meriluoto*

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

84 Citations (Scopus)

Abstract

Mustard (Sinapis alba L.) seeds were cultivated for seven days on a solid nutrient medium supplemented with 0-40μg microcystin-RR per ml. Microcystin-RR affected seedling growth (ic50 0.8μg/ml) and microcystin concentrations ≥5.0μg/ml produced malformed plants. The inhibition of protein phosphatase 1 and 2A activity correlated with the growth inhibition. The seedlings were also shown to take up 3H-dihydromicrocystin-LR derived radioactivity up to a level corresponding to ca. 80ng toxin per mg plant protein. Copyright (C) 1998 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)1921-1926
Number of pages6
JournalToxicon
Volume36
Issue number12
DOIs
Publication statusPublished - Dec 1998
MoE publication typeA1 Journal article-refereed

Fingerprint

Dive into the research topics of 'Microcystin uptake inhibits growth and protein phosphatase activity in mustard (Sinapis alba L.) seedlings'. Together they form a unique fingerprint.

Cite this