Medication Counseling with Large Language Models: Balancing Flexibility and Rigidity

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Abstract

The introduction of large language models (LLMs)
has greatly enhanced the capabilities of software agents. Instead
of relying on rule-based interactions, agents can now interact in
flexible ways akin to humans. However, this flexibility quickly
becomes a problem in fields where errors can be disastrous, such
as in a pharmacy context, but the opposite also holds true; a
system that is too inflexible will also lead to errors, as it can
become too rigid to handle situations that are not accounted
for. Work using LLMs in a pharmacy context have adopted
a wide scope, accounting for many different medications in
brief interactions — our strategy is the opposite: focus on a
more narrow and long task. This not only enables a greater
understanding of the task at hand, but also provides insight into
what challenges are present in an interaction of longer nature.
The main challenge, however, remains the same for a narrow
and wide system: it needs to strike a balance between adherence
to conversational requirements and flexibility. In an effort to
strike such a balance, we propose a system meant to provide
medication counseling while juggling these two extremes. We
also cover our design in constructing such a system, with a focus
on methods aiming to fulfill conversation requirements, reduce
hallucinations and promote high-quality responses. The methods
used have the potential to increase the determinism of the system,
while simultaneously not removing the dynamic conversational
abilities granted by the usage of LLMs. However, a great deal of
work remains ahead, and the development of this kind of system
needs to involve continuous testing and a human-in-the-loop. It
should also be evaluated outside of commonly used benchmarks
for LLMs, as these do not adequately capture the complexities
of this kind of conversational system.
Original languageEnglish
Title of host publication2025 IEEE International Conference on Agentic AI (ICA)
Number of pages6
Publication statusAccepted/In press - 2026
MoE publication typeA4 Article in a conference publication
Event2025 IEEE International Conference on Agentic AI - Wuhan, China
Duration: 5 Dec 20257 Dec 2025
https://attend.ieee.org/ica-2025/

Conference

Conference2025 IEEE International Conference on Agentic AI
Abbreviated titleICA
Country/TerritoryChina
CityWuhan
Period05/12/2507/12/25
Internet address

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