Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, F-18-labeled [Nle(14),Lys(40)]exendin-4 analog, shows promise for clinical imaging

Kirsi Mikkola, Cheng-Bin Yim, Paula Lehtiniemi, Saila Kauhanen, Miikka Tarkia, Tuula Tolvanen, Pirjo Nuutila, Olof Solin

Research output: Contribution to journalArticleScientificpeer-review

16 Citations (Scopus)


Conclusions: [F-18] exendin-4 showed promise as a tracer for clinical imaging of pancreatic beta cells, due to its high specific uptake in native beta cells and its concomitant low kidney radioactivity uptake.
Original languageUndefined/Unknown
Pages (from-to)
Number of pages11
JournalEJNMMI Research
Publication statusPublished - 2016
MoE publication typeA1 Journal article-refereed


  • beta cell
  • Exendin
  • F-18
  • Pancreas
  • PET

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